Methotrexate EP Impurity D

Name: Methotrexate EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-023091

About Methotrexate EP Impurity D

Vaqora Chemicals supplies Methotrexate EP Impurity D, a pharmacopeial impurity of Methotrexate registered under CAS number 5623-18-7. With the molecular formula C15H14N6O3, it has a molar mass of 326.31 g/mol. Its systematic (IUPAC) name is 4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoic acid. Common synonyms include Methotrexate EP Impurity D (Free Base) and Methotrexate - Impurity D.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Methotrexate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Methotrexate EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Methotrexate EP Impurity D
Catalogue No.	VQ-023091
CAS Number	5623-18-7
IUPAC name	4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoic acid
Molecular formula	C₁₅H₁₄N₆O₃
Molecular weight	326.31 g/mol
Exact mass	326.1127
Grade	Reference Standard
HSN code	38229090
InChIKey	QHNLFEQJGRZKTK-UHFFFAOYSA-N
SMILES	CN(CC1=CN=C2C(=N1)C(=O)NC(=N2)N)C3=CC=C(C=C3)C(=O)O
PubChem CID	135441780

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	3 / 7
TPSA	134 Å²
Synonyms	Methotrexate EP Impurity D (Free Base), Methotrexate - Impurity D, Metfol-B, N10-Methylpteroic acid, N(10)-Methylpteroic acid, n(10)-Methyl pteroic acid, p-((N-(2-Amino-4-hydroxy)pteridin-6-ylmethyl)-N-methylamino)benzoic acid, Benzoic acid, p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)methylamino)-, Benzoic acid, 4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)methylamino)-, BENZOIC ACID, p-((N-(2-AMINO-4-HYDROXY)PTERIDIN-6-YLMETHYL)-N-METHYLAMINO)-, Benzoic acid, p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]-, Benzoic acid, p-[[N-(2-amino-4-hydroxy)pteridin-6-ylmethyl]-N-methylamino]-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methotrexate EP Impurity D?

The CAS Registry Number of Methotrexate EP Impurity D is 5623-18-7. It is also known as Methotrexate EP Impurity D (Free Base), Methotrexate - Impurity D, Metfol-B.

What is the molecular formula and molecular weight of Methotrexate EP Impurity D?

Methotrexate EP Impurity D has the molecular formula C15H14N6O3 and a molecular weight of 326.31 g/mol. Its IUPAC name is 4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoic acid.

What is Methotrexate EP Impurity D used for?

Methotrexate EP Impurity D is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methotrexate EP Impurity D can I order?

We supply Methotrexate EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methotrexate EP Impurity D?

Yes. Every lot of Methotrexate EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methotrexate EP Impurity D be shipped internationally?

Yes. We export Methotrexate EP Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.