5-Des-Bromo-macitentan

Name: 5-Des-Bromo-macitentan
Brand: Vaqora Chemicals
SKU: VQ-023025

About 5-Des-Bromo-macitentan

Vaqora Chemicals supplies 5-Des-Bromo-macitentan, an impurity of Macitentan registered under CAS number 2211059-00-4. Its molecular formula is C19H21BrN6O4S and its molecular weight is 509.4 g/mol. Its systematic (IUPAC) name is 5-(4-bromophenyl)-N-(propylsulfamoyl)-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-amine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Macitentan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 5-Des-Bromo-macitentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Des-Bromo-macitentan
Catalogue No.	VQ-023025
CAS Number	2211059-00-4
IUPAC name	5-(4-bromophenyl)-N-(propylsulfamoyl)-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-amine
Molecular formula	C₁₉H₂₁BrN₆O₄S
Molecular weight	509.4 g/mol
Exact mass	508.0528
Grade	Reference Standard
HSN code	38229090
InChIKey	CKHUTZYQJNMFJR-UHFFFAOYSA-N
SMILES	CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=CC=N2)C3=CC=C(C=C3)Br
PubChem CID	168429883

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 10
TPSA	137 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Des-Bromo-macitentan?

The CAS Registry Number of 5-Des-Bromo-macitentan is 2211059-00-4. It is also known as N-[5-(4-Bromophenyl)-6-[2-(2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-N'-propyl-sulfamide.

What is the molecular formula and molecular weight of 5-Des-Bromo-macitentan?

5-Des-Bromo-macitentan has the molecular formula C19H21BrN6O4S and a molecular weight of 509.4 g/mol. Its IUPAC name is 5-(4-bromophenyl)-N-(propylsulfamoyl)-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-amine.

What is 5-Des-Bromo-macitentan used for?

5-Des-Bromo-macitentan is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Des-Bromo-macitentan can I order?

We supply 5-Des-Bromo-macitentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Des-Bromo-macitentan?

Yes. Every lot of 5-Des-Bromo-macitentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Des-Bromo-macitentan be shipped internationally?

Yes. We export 5-Des-Bromo-macitentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.