O,O'-Bis(5-Bromopyrimidin-2-yl)glycol

Name: O,O'-Bis(5-Bromopyrimidin-2-yl)glycol
Brand: Vaqora Chemicals
SKU: VQ-023018

About O,O'-Bis(5-Bromopyrimidin-2-yl)glycol

O,O'-Bis(5-Bromopyrimidin-2-yl)glycol is an impurity of Macitentan carrying the CAS registry number 2211054-90-7. With the molecular formula C10H8Br2N4O2, it has a molar mass of 376.0 g/mol. The IUPAC name is 5-bromo-2-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidine. It is also known as 1,2-bis((5-bromopyrimidin-2-yl)oxy)ethane.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Macitentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer O,O'-Bis(5-Bromopyrimidin-2-yl)glycol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	O,O'-Bis(5-Bromopyrimidin-2-yl)glycol
Catalogue No.	VQ-023018
CAS Number	2211054-90-7
IUPAC name	5-bromo-2-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidine
Molecular formula	C₁₀H₈Br₂N₄O₂
Molecular weight	376 g/mol
Exact mass	375.8994
Grade	Reference Standard
HSN code	38229090
InChIKey	ITCWLFQPBZOBCV-UHFFFAOYSA-N
SMILES	C1=C(C=NC(=N1)OCCOC2=NC=C(C=N2)Br)Br
PubChem CID	132278565

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	0 / 6
TPSA	70 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O,O'-Bis(5-Bromopyrimidin-2-yl)glycol?

The CAS Registry Number of O,O'-Bis(5-Bromopyrimidin-2-yl)glycol is 2211054-90-7. It is also known as 1,2-bis((5-bromopyrimidin-2-yl)oxy)ethane, 2,2'-[ethane-1,2-diylbis(oxy)]bis(5-bromopyrimidine).

What is the molecular formula and molecular weight of O,O'-Bis(5-Bromopyrimidin-2-yl)glycol?

O,O'-Bis(5-Bromopyrimidin-2-yl)glycol has the molecular formula C10H8Br2N4O2 and a molecular weight of 376 g/mol. Its IUPAC name is 5-bromo-2-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidine.

What is O,O'-Bis(5-Bromopyrimidin-2-yl)glycol used for?

O,O'-Bis(5-Bromopyrimidin-2-yl)glycol is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O,O'-Bis(5-Bromopyrimidin-2-yl)glycol can I order?

We supply O,O'-Bis(5-Bromopyrimidin-2-yl)glycol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O,O'-Bis(5-Bromopyrimidin-2-yl)glycol?

Yes. Every lot of O,O'-Bis(5-Bromopyrimidin-2-yl)glycol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O,O'-Bis(5-Bromopyrimidin-2-yl)glycol be shipped internationally?

Yes. We export O,O'-Bis(5-Bromopyrimidin-2-yl)glycol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.