N-Despropyl-N-Methyl Macitentan

Name: N-Despropyl-N-Methyl Macitentan
Brand: Vaqora Chemicals
SKU: VQ-023024

About N-Despropyl-N-Methyl Macitentan

N-Despropyl-N-Methyl Macitentan (CAS 441798-25-0) is a metabolite or degradation product of Macitentan offered by Vaqora Chemicals. The compound has the formula C17H16Br2N6O4S, corresponding to a molecular weight of 560.2 g/mol. Systematically, it is named 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(methylsulfamoyl)pyrimidin-4-amine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Macitentan, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Despropyl-N-Methyl Macitentan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Despropyl-N-Methyl Macitentan
Catalogue No.	VQ-023024
CAS Number	441798-25-0
IUPAC name	5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(methylsulfamoyl)pyrimidin-4-amine
Molecular formula	C₁₇H₁₆Br₂N₆O₄S
Molecular weight	560.2 g/mol
Exact mass	559.93
Grade	Reference Standard
HSN code	38229090
InChIKey	BRSITRUZDCGGKH-UHFFFAOYSA-N
SMILES	CNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
PubChem CID	21041267

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 10
TPSA	137 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Despropyl-N-Methyl Macitentan?

The CAS Registry Number of N-Despropyl-N-Methyl Macitentan is 441798-25-0.

What is the molecular formula and molecular weight of N-Despropyl-N-Methyl Macitentan?

N-Despropyl-N-Methyl Macitentan has the molecular formula C17H16Br2N6O4S and a molecular weight of 560.2 g/mol. Its IUPAC name is 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(methylsulfamoyl)pyrimidin-4-amine.

What is N-Despropyl-N-Methyl Macitentan used for?

N-Despropyl-N-Methyl Macitentan is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Despropyl-N-Methyl Macitentan can I order?

We supply N-Despropyl-N-Methyl Macitentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Despropyl-N-Methyl Macitentan?

Yes. Every lot of N-Despropyl-N-Methyl Macitentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Despropyl-N-Methyl Macitentan be shipped internationally?

Yes. We export N-Despropyl-N-Methyl Macitentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.