(6S)-Tetrahydrofolic Acid

Name: (6S)-Tetrahydrofolic Acid
Brand: Vaqora Chemicals
SKU: VQ-030858

About (6S)-Tetrahydrofolic Acid

(6S)-Tetrahydrofolic Acid is an impurity of Folinic Acid carrying the CAS registry number 71963-69-4. With the molecular formula C19H23N7O6, it has a molar mass of 445.4 g/mol. It is also known as (6S)-H4folate or (6S)-5,6,7,8-tetrahydrofolic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Folinic Acid, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (6S)-Tetrahydrofolic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Folinic Acid

View every impurity, metabolite and intermediate we list for Folinic Acid.

Folinic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	(6S)-Tetrahydrofolic Acid
Catalogue No.	VQ-030858
CAS Number	71963-69-4
IUPAC name	(2S)-2-[[4-[[(6S)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₁₉H₂₃N₇O₆
Molecular weight	445.4 g/mol
Exact mass	445.171
Grade	Reference Standard
HSN code	38229090
InChIKey	MSTNYGQPCMXVAQ-RYUDHWBXSA-N
SMILES	C1[C@@H](NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	135398650

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	8 / 10
TPSA	207 Å²
Synonyms	(6S)-H4folate, (6S)-5,6,7,8-tetrahydrofolic acid, (6S)-5,6,7,8-tetrahydropteroylglutamate, N-(5,6,7,8-tetrahydropteroyl)-L-glutamic acid, (6S)-tetrahydrofolate, (6S)-THFA, tetrahydrofolic-acid, (2S,6S)-5,6,7,8-tetrahydrofolic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (6S)-Tetrahydrofolic Acid?

The CAS Registry Number of (6S)-Tetrahydrofolic Acid is 71963-69-4. It is also known as (6S)-H4folate, (6S)-5,6,7,8-tetrahydrofolic acid, (6S)-5,6,7,8-tetrahydropteroylglutamate.

What is the molecular formula and molecular weight of (6S)-Tetrahydrofolic Acid?

(6S)-Tetrahydrofolic Acid has the molecular formula C19H23N7O6 and a molecular weight of 445.4 g/mol. Its IUPAC name is (2S)-2-[[4-[[(6S)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid.

What is (6S)-Tetrahydrofolic Acid used for?

(6S)-Tetrahydrofolic Acid is supplied as a characterised reference material related to Folinic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (6S)-Tetrahydrofolic Acid can I order?

We supply (6S)-Tetrahydrofolic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (6S)-Tetrahydrofolic Acid?

Yes. Every lot of (6S)-Tetrahydrofolic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (6S)-Tetrahydrofolic Acid be shipped internationally?

Yes. We export (6S)-Tetrahydrofolic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.