Folinic Acid EP Impurity B

Name: Folinic Acid EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022713

About Folinic Acid EP Impurity B

Listed under CAS 98814-60-9, Folinic Acid EP Impurity B is a pharmacopeial impurity of Folinic Acid available from Vaqora Chemicals. Its molecular formula is C21H23N7O8 and its molecular weight is 501.4 g/mol. Alternative names: Levofolinate EP Impurity B and Folinic Acid Impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Folinic Acid impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Folinic Acid EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Folinic Acid

View every impurity, metabolite and intermediate we list for Folinic Acid.

Folinic Acid impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Folinic Acid EP Impurity B
Catalogue No.	VQ-022713
CAS Number	98814-60-9
IUPAC name	(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₁H₂₃N₇O₈
Molecular weight	501.4 g/mol
Exact mass	501.1608
Grade	Reference Standard
HSN code	38229090
InChIKey	NQACWOLNMUVBMP-KZUDCZAMSA-N
SMILES	C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CN(C=O)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	139025760

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.9
H-bond donors / acceptors	6 / 10
TPSA	224 Å²
Synonyms	Levofolinate EP Impurity B, Folinic Acid Impurity B, Calcium Levofolinate Pentahydrate - Impurity B, N5,N10-diformyl-tetrahydrofolic acid, 5,10-Diformyl-5,6,7,8-tetrahydro Folic Acid Calcium Salt Hydrate, 5,10-Diformyl-(6S)-tetrahydrofolic acid

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Folinic Acid EP Impurity B?

The CAS Registry Number of Folinic Acid EP Impurity B is 98814-60-9. It is also known as Levofolinate EP Impurity B, Folinic Acid Impurity B, Calcium Levofolinate Pentahydrate - Impurity B.

What is the molecular formula and molecular weight of Folinic Acid EP Impurity B?

Folinic Acid EP Impurity B has the molecular formula C21H23N7O8 and a molecular weight of 501.4 g/mol. Its IUPAC name is (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid.

What is Folinic Acid EP Impurity B used for?

Folinic Acid EP Impurity B is supplied as a characterised reference material related to Folinic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Folinic Acid EP Impurity B can I order?

We supply Folinic Acid EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Folinic Acid EP Impurity B?

Yes. Every lot of Folinic Acid EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Folinic Acid EP Impurity B be shipped internationally?

Yes. Folinic Acid EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.