Amitriptyline HCl

Name: Amitriptyline HCl
Brand: Vaqora Chemicals
SKU: VQ-004021

About Amitriptyline HCl

Amitriptyline HCl (CAS 549-18-8) is a central nervous system API offered by Vaqora Chemicals (IP/BP/USP grade). With the molecular formula C20H24ClN, it has a molar mass of 313.9 g/mol. The IUPAC name is N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine. Hydrochloride. It is also known as Amitriptyline hydrochloride or Saroten Retard.

The product is provided as a crystalline solid. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Danger” with 9 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our CNS and psychiatric APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Our customers for this product work in pharmaceutical manufacturing.

We offer Amitriptyline HCl in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amitriptyline HCl
Catalogue No.	VQ-004021
CAS Number	549-18-8
IUPAC name	N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydrochloride
Molecular formula	C₂₀H₂₄ClN
Molecular weight	313.9 g/mol
Exact mass	313.1597
Grade	IP/BP/USP
HSN code	2933
InChIKey	KFYRPLNVJVHZGT-UHFFFAOYSA-N
SMILES	CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
PubChem CID	11065

Physical properties
Physical form	Crystalline
Appearance	White or practically white, odorless or practically odorless, crystalline powder or small crystals
H-bond donors / acceptors	1 / 1
TPSA	3.2 Å²
Synonyms	Amitriptyline hydrochloride, Saroten Retard, Amitriptylini hydrochloridum, Cytriptyline, Triptafen-m, Limbitrol 5, Tryptizol-75, Sentravil PM-25, Elavil 25 mg, Annoyltin, Domical, Elavil hydrochloride

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H318Causes serious eye damage
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H370Causes damage to organs
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P264 + P265, P270, P273, P280, P301 + P316, P301 + P317, P305 + P351 + P338, P305 + P354 + P338, P308 + P316, P317, P318, P321, P330, P337 + P317, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 549-18-8

Biochemistry

Amitriptyline HCl, for biochemistry

CAS: 549-18-8
Formula: C₂₀H₂₄ClN
MW: 313.9 g/mol

VQ-045696

Frequently asked questions

What is the CAS number of Amitriptyline HCl?

The CAS Registry Number of Amitriptyline HCl is 549-18-8. It is also known as Amitriptyline hydrochloride, Saroten Retard, Amitriptylini hydrochloridum.

What is the molecular formula and molecular weight of Amitriptyline HCl?

Amitriptyline HCl has the molecular formula C20H24ClN and a molecular weight of 313.9 g/mol.

Which grade and pack sizes of Amitriptyline HCl can I order?

We supply Amitriptyline HCl in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amitriptyline HCl?

Yes. Every lot of Amitriptyline HCl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amitriptyline HCl be shipped internationally?

Yes. Amitriptyline HCl is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.