Amlodipine

Name: Amlodipine
Brand: Vaqora Chemicals
SKU: VQ-004078

About Amlodipine

Amlodipine (CAS 88150-42-9) is a cardiovascular API offered by Vaqora Chemicals (IP/BP/USP grade). With the molecular formula C20H25ClN2O5, it has a molar mass of 408.9 g/mol. The IUPAC name is 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. Common synonyms include Amlodipine Free Base and HGP-0904.

It is supplied as a white to off-white crystalline powder. Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our cardiovascular and antihypertensive APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Buyers come mainly from pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Amlodipine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Amlodipine

View every impurity, metabolite and intermediate we list for Amlodipine.

Amlodipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amlodipine
Catalogue No.	VQ-004078
CAS Number	88150-42-9
IUPAC name	3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₂₀H₂₅ClN₂O₅
Molecular weight	408.9 g/mol
Exact mass	408.1452
Grade	IP/BP/USP
HSN code	2933
InChIKey	HTIQEAQVCYTUBX-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
PubChem CID	2162

Physical properties
Physical form	Powder
Appearance	White to off-white crystalline powder
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 7
TPSA	99.9 Å²
Synonyms	Amlodipine Free Base, HGP-0904, Astudal 5, Amlodipine Maleate (1:1), Istin, Norvasc (TN), Coroval, Racemic Amlodipine, C20H25ClN2O5, 88150-42-9 (free base), Amlodipine (Standard), Amlodipine (USP/INN)

Safety & hazard information (GHS)

Corrosive

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H318Causes serious eye damage
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P264 + P265, P270, P273, P280, P301 + P316, P305 + P354 + P338, P317, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 88150-42-9

Reference Standard

Amlodipine WS

CAS: 88150-42-9
Formula: C₂₀H₂₅ClN₂O₅
MW: 408.9 g/mol

VQ-007312

Frequently asked questions

What is the CAS number of Amlodipine?

The CAS Registry Number of Amlodipine is 88150-42-9. It is also known as Amlodipine Free Base, HGP-0904, Astudal 5.

What is the molecular formula and molecular weight of Amlodipine?

Amlodipine has the molecular formula C20H25ClN2O5 and a molecular weight of 408.9 g/mol. Its IUPAC name is 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.

What is Amlodipine used for?

Amlodipine is supplied as a characterised reference material related to Amlodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amlodipine can I order?

We supply Amlodipine in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amlodipine?

Yes. Every lot of Amlodipine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amlodipine be shipped internationally?

Yes. Amlodipine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.