Anastrozole

Name: Anastrozole
Brand: Vaqora Chemicals
SKU: VQ-004210

About Anastrozole

Anastrozole is an anticancer API (IP/BP/USP grade) carrying the CAS registry number 120511-73-1, specified at ≥99.5% purity. Formula C17H19N5, molecular weight 293.4 g/mol. Systematically, it is named 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile. It is also known as Anastrozol or ICI D1033.

In its supplied form it is a white crystalline powder. Keep the container tightly sealed and store it in a cool, dry area. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our oncology APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Typical end-use sectors are pharmaceutical manufacturing.

We offer Anastrozole in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Polymer & resin production
Pharmaceutical formulation

Industries

Related to Anastrozole

View every impurity, metabolite and intermediate we list for Anastrozole.

Anastrozole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Anastrozole
Catalogue No.	VQ-004210
CAS Number	120511-73-1
IUPAC name	2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
Molecular formula	C₁₇H₁₉N₅
Molecular weight	293.4 g/mol
Exact mass	293.164
Grade	IP/BP/USP
Purity / assay	≥99.5%
HSN code	2933
InChIKey	YBBLVLTVTVSKRW-UHFFFAOYSA-N
SMILES	CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N
PubChem CID	2187

Physical properties
Physical form	Powder
Appearance	White crystalline powder
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 4
TPSA	78.3 Å²
Synonyms	Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile, Anastrozol, ICI D1033, Zeneca ZD 1033, 2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile, Anastrozole Tablets, 2-(3-(1-Cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl)-2-methylpropanenitrile, 2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile), 2,2'-(5-(1H-1,2,4-Triazol-1-ylmethyl)-1,3-phenylene)di(2-methylpropionitrile), 2,2'-(5-((1H-1,2,4-triazol-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile), 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile), 2-[3-(2-cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H351Suspected of causing cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P316, P301 + P317, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 120511-73-1

Reference Standard

Anastrozole WS

CAS: 120511-73-1
Formula: C₁₇H₁₉N₅
MW: 293.4 g/mol

In stock

Frequently asked questions

What is the CAS number of Anastrozole?

The CAS Registry Number of Anastrozole is 120511-73-1. It is also known as Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile, Anastrozol, ICI D1033.

What is the molecular formula and molecular weight of Anastrozole?

Anastrozole has the molecular formula C17H19N5 and a molecular weight of 293.4 g/mol. Its IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile.

What is Anastrozole used for?

Anastrozole is supplied as a characterised reference material related to Anastrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Anastrozole can I order?

We supply Anastrozole in IP/BP/USP (≥99.5%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Anastrozole?

Yes. Every lot of Anastrozole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Anastrozole be shipped internationally?

Yes. Anastrozole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.