Aprepitant EP Impurity B

Name: Aprepitant EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-029203

About Aprepitant EP Impurity B

Listed under CAS 2348441-62-1, Aprepitant EP Impurity B is a pharmacopeial impurity of Aprepitant available from Vaqora Chemicals. With the molecular formula C29H25F7N4O3, it has a molar mass of 610.5 g/mol. It is also known as Aprepitant - Impurity B or 4-Defluoro-3-(p-fluorophenyl) Aprepitant.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Aprepitant impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Aprepitant EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Aprepitant EP Impurity B
Catalogue No.	VQ-029203
CAS Number	2348441-62-1
IUPAC name	3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-[3-(4-fluorophenyl)phenyl]morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Molecular formula	C₂₉H₂₅F₇N₄O₃
Molecular weight	610.5 g/mol
Exact mass	610.1815
Grade	Reference Standard
HSN code	38229090
InChIKey	QIEHKJXOBWMTEV-RENKICTCSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=CC(=C4)C5=CC=C(C=C5)F
PubChem CID	156596420

Physical properties
Physical form	Solid
LogP (XLogP3)	5.8
H-bond donors / acceptors	2 / 12
TPSA	75.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprepitant EP Impurity B?

The CAS Registry Number of Aprepitant EP Impurity B is 2348441-62-1. It is also known as Aprepitant - Impurity B, 4-Defluoro-3-(p-fluorophenyl) Aprepitant, Fosaprepitant Impurity 63.

What is the molecular formula and molecular weight of Aprepitant EP Impurity B?

Aprepitant EP Impurity B has the molecular formula C29H25F7N4O3 and a molecular weight of 610.5 g/mol. Its IUPAC name is 3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-[3-(4-fluorophenyl)phenyl]morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one.

What is Aprepitant EP Impurity B used for?

Aprepitant EP Impurity B is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprepitant EP Impurity B can I order?

We supply Aprepitant EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprepitant EP Impurity B?

Yes. Every lot of Aprepitant EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprepitant EP Impurity B be shipped internationally?

Yes. We export Aprepitant EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.