Ascomycin

Name: Ascomycin
Brand: Vaqora Chemicals
SKU: VQ-028165

About Ascomycin

Listed under CAS 104987-12-4, Ascomycin is an impurity of Tacrolimus available from Vaqora Chemicals. The compound has the formula C43H69NO12, corresponding to a molecular weight of 792.0 g/mol. It is also known as Immunomycin or Changchuanmycin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Tacrolimus impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ascomycin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	Ascomycin
Catalogue No.	VQ-028165
CAS Number	104987-12-4
IUPAC name	(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-ethyl-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₃H₆₉NO₁₂
Molecular weight	792 g/mol
Exact mass	791.482
Grade	Reference Standard
HSN code	38229090
InChIKey	ZDQSOHOQTUFQEM-NURRSENYSA-N
SMILES	CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C
PubChem CID	5282071

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	3 / 12
TPSA	178 Å²
Synonyms	Immunomycin, Changchuanmycin, FK-520, FR-520, FK 520, EX-A1796, FR 520, Fermentation product from Streptomyces hygroscopicus, Ascomycin, Streptomyces hygroscopicus var ascomyceticus, Ascomycin from Streptomyces hygroscopicus var. ascomyceticus

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ascomycin?

The CAS Registry Number of Ascomycin is 104987-12-4. It is also known as Immunomycin, Changchuanmycin, FK-520.

What is the molecular formula and molecular weight of Ascomycin?

Ascomycin has the molecular formula C43H69NO12 and a molecular weight of 792 g/mol.

What is Ascomycin used for?

Ascomycin is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ascomycin can I order?

We supply Ascomycin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ascomycin?

Yes. Every lot of Ascomycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ascomycin be shipped internationally?

Yes. Ascomycin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.