Auristatin E

Name: Auristatin E
Brand: Vaqora Chemicals
SKU: VQ-035861

About Auristatin E

Auristatin E is an impurity of Auristatin carrying the CAS registry number 160800-57-7. The compound has the formula C40H69N5O7, corresponding to a molecular weight of 732.0 g/mol. Common synonyms include Auristatin E (GMP) and EX-A3360.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Auristatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Auristatin E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Auristatin

View every impurity, metabolite and intermediate we list for Auristatin.

Auristatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Auristatin E
Catalogue No.	VQ-035861
CAS Number	160800-57-7
IUPAC name	(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide
Molecular formula	C₄₀H₆₉N₅O₇
Molecular weight	732 g/mol
Exact mass	731.5197
Grade	Reference Standard
HSN code	38229090
InChIKey	WOWDZACBATWTAU-FEFUEGSOSA-N
SMILES	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C
PubChem CID	11498622

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	3 / 8
TPSA	141 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Auristatin E?

The CAS Registry Number of Auristatin E is 160800-57-7. It is also known as Auristatin E (GMP), EX-A3360.

What is the molecular formula and molecular weight of Auristatin E?

Auristatin E has the molecular formula C40H69N5O7 and a molecular weight of 732 g/mol.

What is Auristatin E used for?

Auristatin E is supplied as a characterised reference material related to Auristatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Auristatin E can I order?

We supply Auristatin E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Auristatin E?

Yes. Every lot of Auristatin E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Auristatin E be shipped internationally?

Yes. Auristatin E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.