Monomethylauristatin E D8

Name: Monomethylauristatin E D8
Brand: Vaqora Chemicals
SKU: VQ-036773

About Monomethylauristatin E D8

Vaqora Chemicals supplies Monomethylauristatin E D8, a stable isotope labelled analogue related to Auristatin registered under CAS number 2070009-72-0. Its molecular formula is C39H67N5O7 and its molecular weight is 726.0 g/mol. Alternative names: D8-MMAE and MMAE-d8.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Monomethylauristatin E D8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Auristatin

View every impurity, metabolite and intermediate we list for Auristatin.

Auristatin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Monomethylauristatin E D8
Catalogue No.	VQ-036773
CAS Number	2070009-72-0
IUPAC name	(2S)-2,3,4,4,4-pentadeuterio-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]-3-(trideuteriomethyl)butanamide
Molecular formula	C₃₉H₆₇N₅O₇
Molecular weight	726 g/mol
Exact mass	725.5543
Grade	Reference Standard
HSN code	38229090
InChIKey	DASWEROEPLKSEI-CMHCZSPYSA-N
SMILES	[2H][C@@](C(=O)N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])NC(=O)[C@H](C(C)C)NC
PubChem CID	78357789

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	4 / 8
TPSA	150 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Monomethylauristatin E D8?

The CAS Registry Number of Monomethylauristatin E D8 is 2070009-72-0. It is also known as D8-MMAE, MMAE-d8, EX-A4341.

What is the molecular formula and molecular weight of Monomethylauristatin E D8?

Monomethylauristatin E D8 has the molecular formula C39H67N5O7 and a molecular weight of 726 g/mol.

What is Monomethylauristatin E D8 used for?

Monomethylauristatin E D8 is supplied as a characterised reference material related to Auristatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Monomethylauristatin E D8 can I order?

We supply Monomethylauristatin E D8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Monomethylauristatin E D8?

Yes. Every lot of Monomethylauristatin E D8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Monomethylauristatin E D8 be shipped internationally?

Yes. We export Monomethylauristatin E D8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.