Betamethasone

Name: Betamethasone
Brand: Vaqora Chemicals
SKU: VQ-004118

About Betamethasone

Listed under CAS 378-44-9, Betamethasone is a metabolic / hormonal API available from Vaqora Chemicals in IP/BP/USP grade. With the molecular formula C22H29FO5, it has a molar mass of 392.5 g/mol. Alternative names: Betadexamethasone and Flubenisolone.

The product is provided as a powder. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our antidiabetic, hormone and metabolic APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Our customers for this product work in pharmaceutical manufacturing.

We offer Betamethasone in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Betamethasone

View every impurity, metabolite and intermediate we list for Betamethasone.

Betamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Betamethasone
Catalogue No.	VQ-004118
CAS Number	378-44-9
IUPAC name	(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₉FO₅
Molecular weight	392.5 g/mol
Exact mass	392.1999
Grade	IP/BP/USP
InChIKey	UREBDLICKHMUKA-DVTGEIKXSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
PubChem CID	9782

Physical properties
Physical form	Powder
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 6
TPSA	94.8 Å²
Synonyms	Betadexamethasone, Flubenisolone, Celestene, beta-Methasone, Desacort-Beta, Betametasone, beta-Methasone alcohol, SCH 4831, 9-Fluoro-16beta-methylprednisolone, 9alpha-Fluoro-16beta-methylprednisolone, SCH-4831, 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H330Fatal if inhaled
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P271, P273, P280, P284, P304 + P340, P316, P318, P319, P320, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Betamethasone?

The CAS Registry Number of Betamethasone is 378-44-9. It is also known as Betadexamethasone, Flubenisolone, Celestene.

What is the molecular formula and molecular weight of Betamethasone?

Betamethasone has the molecular formula C22H29FO5 and a molecular weight of 392.5 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.

What is Betamethasone used for?

Betamethasone is supplied as a characterised reference material related to Betamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Betamethasone can I order?

We supply Betamethasone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Betamethasone?

Yes. Every lot of Betamethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Betamethasone be shipped internationally?

Yes. Betamethasone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.