Bortezomib

Name: Bortezomib
Brand: Vaqora Chemicals
SKU: VQ-004211

About Bortezomib

Bortezomib is an anticancer API (IP/BP/USP grade) carrying the CAS registry number 179324-69-7. Formula C19H25BN4O4, molecular weight 384.2 g/mol. Its systematic (IUPAC) name is [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid. Alternative names: PS-341 and LDP-341.

It is supplied as a white or almost white powder. Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our oncology APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Typical end-use sectors are pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Bortezomib is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Bortezomib
Catalogue No.	VQ-004211
CAS Number	179324-69-7
IUPAC name	[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
Molecular formula	C₁₉H₂₅BN₄O₄
Molecular weight	384.2 g/mol
Exact mass	384.1969
Grade	IP/BP/USP
HSN code	2933
InChIKey	GXJABQQUPOEUTA-RDJZCZTQSA-N
SMILES	B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
PubChem CID	387447

Physical properties
Physical form	Powder
Appearance	White or almost white powder
H-bond donors / acceptors	4 / 6
TPSA	124 Å²
Synonyms	PS-341, LDP-341, LDP 341, Bortezomib accord, N-((1R)-1-(DIHYDROXYBORYL)-3-methylbutyl)-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide, 341, PS, Bortezomib for Injection, ((1R)-3-methyl-1-((2S)-3-phenyl-2-(pyrazin-2-ylformamido)propanamido)butyl)boronic acid, Bortezomib (PS-341), Ps 341, ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid, MLN-341

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P273, P280, P301 + P316, P302 + P352, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bortezomib?

The CAS Registry Number of Bortezomib is 179324-69-7. It is also known as PS-341, LDP-341, LDP 341.

What is the molecular formula and molecular weight of Bortezomib?

Bortezomib has the molecular formula C19H25BN4O4 and a molecular weight of 384.2 g/mol. Its IUPAC name is [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid.

What is Bortezomib used for?

Bortezomib is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bortezomib can I order?

We supply Bortezomib in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bortezomib?

Yes. Every lot of Bortezomib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bortezomib be shipped internationally?

Yes. Bortezomib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.