Bortezomib Impurity A

Name: Bortezomib Impurity A
Brand: Vaqora Chemicals
SKU: VQ-020684

About Bortezomib Impurity A

Listed under CAS 289472-80-6, Bortezomib Impurity A is an impurity of Bortezomib available from Vaqora Chemicals. Formula C14H14N4O2, molecular weight 270.29 g/mol. Its systematic (IUPAC) name is N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. Alternative names: Bortezomib USP Impurity B and Bortezomib amide impurity.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Bortezomib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	Bortezomib Impurity A
Catalogue No.	VQ-020684
CAS Number	289472-80-6
IUPAC name	N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Molecular formula	C₁₄H₁₄N₄O₂
Molecular weight	270.29 g/mol
Exact mass	270.1117
Grade	Reference Standard
HSN code	38229090
InChIKey	KTQJEBWLYWKXRA-NSHDSACASA-N
SMILES	C1=CC=C(C=C1)C[C@@H](C(=O)N)NC(=O)C2=NC=CN=C2
PubChem CID	67121778

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	2 / 4
TPSA	98 Å²
Synonyms	N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide, Bortezomib USP Impurity B, Bortezomib amide impurity, Bortezomib Related Compound B, (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide, Bortezomib Impurity C, Bortezomib (m3), N-((1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl)-pyrazinecarboxamide, 2-Pyrazinecarboxamide, N-((1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl)-, 2-Pyrazinecarboxamide, N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]-, N-((1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl)-pyrazinecarboxamide, (-)-, N-[(1S)-2-Amino-1-benzyl-2-oxoethyl]pyrazine-2-carboxamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bortezomib Impurity A?

The CAS Registry Number of Bortezomib Impurity A is 289472-80-6. It is also known as N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide, Bortezomib USP Impurity B, Bortezomib amide impurity.

What is the molecular formula and molecular weight of Bortezomib Impurity A?

Bortezomib Impurity A has the molecular formula C14H14N4O2 and a molecular weight of 270.29 g/mol. Its IUPAC name is N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.

What is Bortezomib Impurity A used for?

Bortezomib Impurity A is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bortezomib Impurity A can I order?

We supply Bortezomib Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bortezomib Impurity A?

Yes. Every lot of Bortezomib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bortezomib Impurity A be shipped internationally?

Yes. We export Bortezomib Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.