(R)-Hydroxy Des(boric Acid) Bortezomib

Name: (R)-Hydroxy Des(boric Acid) Bortezomib
Brand: Vaqora Chemicals
SKU: VQ-021860

About (R)-Hydroxy Des(boric Acid) Bortezomib

(R)-Hydroxy Des(boric Acid) Bortezomib is a metabolite or degradation product of Bortezomib carrying the CAS registry number 289472-78-2. Its molecular formula is C19H24N4O3 and its molecular weight is 356.4 g/mol. The IUPAC name is N-[(2S)-1-[[(1R)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. It is also known as Hydroxy des(boric acid) bortezomib, (R)- or Bortezomib (m1).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bortezomib, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Hydroxy Des(boric Acid) Bortezomib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Hydroxy Des(boric Acid) Bortezomib
Catalogue No.	VQ-021860
CAS Number	289472-78-2
IUPAC name	N-[(2S)-1-[[(1R)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Molecular formula	C₁₉H₂₄N₄O₃
Molecular weight	356.4 g/mol
Exact mass	356.1848
Grade	Reference Standard
HSN code	38229090
InChIKey	NEIDLJIPMZVISC-DOTOQJQBSA-N
SMILES	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)O
PubChem CID	71607433

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 5
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Hydroxy Des(boric Acid) Bortezomib?

The CAS Registry Number of (R)-Hydroxy Des(boric Acid) Bortezomib is 289472-78-2. It is also known as (S,R)-Bortezomib Hydroxyisopentyl Amide Analog, Hydroxy des(boric acid) bortezomib, (R)-, Bortezomib (m1).

What is the molecular formula and molecular weight of (R)-Hydroxy Des(boric Acid) Bortezomib?

(R)-Hydroxy Des(boric Acid) Bortezomib has the molecular formula C19H24N4O3 and a molecular weight of 356.4 g/mol. Its IUPAC name is N-[(2S)-1-[[(1R)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.

What is (R)-Hydroxy Des(boric Acid) Bortezomib used for?

(R)-Hydroxy Des(boric Acid) Bortezomib is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Hydroxy Des(boric Acid) Bortezomib can I order?

We supply (R)-Hydroxy Des(boric Acid) Bortezomib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Hydroxy Des(boric Acid) Bortezomib?

Yes. Every lot of (R)-Hydroxy Des(boric Acid) Bortezomib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Hydroxy Des(boric Acid) Bortezomib be shipped internationally?

Yes. We export (R)-Hydroxy Des(boric Acid) Bortezomib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.