Bortezomib Impurity G

Name: Bortezomib Impurity G
Brand: Vaqora Chemicals
SKU: VQ-020973

About Bortezomib Impurity G

Bortezomib Impurity G is a metabolite or degradation product of Bortezomib carrying the CAS registry number 289472-81-7. Formula C19H24N4O3, molecular weight 356.4 g/mol. The IUPAC name is N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. It is also known as (S)-Hydroxy Des(boric Acid) Bortezomib or Bortezomib USP Impurity J.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bortezomib, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Bortezomib Impurity G in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	Bortezomib Impurity G
Catalogue No.	VQ-020973
CAS Number	289472-81-7
IUPAC name	N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Molecular formula	C₁₉H₂₄N₄O₃
Molecular weight	356.4 g/mol
Exact mass	356.1848
Grade	Reference Standard
HSN code	38229090
InChIKey	NEIDLJIPMZVISC-RDJZCZTQSA-N
SMILES	CC(C)C[C@@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)O
PubChem CID	71607434

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 5
TPSA	104 Å²
Synonyms	(S)-Hydroxy Des(boric Acid) Bortezomib, Bortezomib USP Impurity J, (S,S)-Bortezomib Hydroxyisopentyl Amide Analog, Bortezomib Impurity D, Bortezomib (m2), Bortezomib Impurity B, Hydroxy des(boric acid) bortezomib, (S)-, N-[(1S)-1-Hydroxy-3-methylbutyl]-Nalpha-(pyrazine-2-carbonyl)-L-phenylalaninamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bortezomib Impurity G?

The CAS Registry Number of Bortezomib Impurity G is 289472-81-7. It is also known as (S)-Hydroxy Des(boric Acid) Bortezomib, Bortezomib USP Impurity J, (S,S)-Bortezomib Hydroxyisopentyl Amide Analog.

What is the molecular formula and molecular weight of Bortezomib Impurity G?

Bortezomib Impurity G has the molecular formula C19H24N4O3 and a molecular weight of 356.4 g/mol. Its IUPAC name is N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.

What is Bortezomib Impurity G used for?

Bortezomib Impurity G is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bortezomib Impurity G can I order?

We supply Bortezomib Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bortezomib Impurity G?

Yes. Every lot of Bortezomib Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bortezomib Impurity G be shipped internationally?

Yes. We export Bortezomib Impurity G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.