Brimonidine

Name: Brimonidine
Brand: Vaqora Chemicals
SKU: VQ-004231

About Brimonidine

Listed under CAS 70359-46-5, Brimonidine is an active pharmaceutical ingredient available from Vaqora Chemicals (IP/BP/USP grade). With the molecular formula C15H16BrN5O6, it has a molar mass of 442.22 g/mol. The IUPAC name is 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine, (2R,3R)-2,3-dihydroxybutanedioic acid. It is also known as Brominide tartrate or Bromoxidine tartrate.

In its supplied form it is a white to slightly yellowish powder. Store in a tightly closed container in a cool, dry and well-ventilated place. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As an active pharmaceutical ingredient within our vitamins, excipients and other APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

We offer Brimonidine in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development
Nutraceutical & excipient use

Industries

Related to Brimonidine

View every impurity, metabolite and intermediate we list for Brimonidine.

Brimonidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Brimonidine
Catalogue No.	VQ-004231
CAS Number	70359-46-5
IUPAC name	5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine;(2R,3R)-2,3-dihydroxybutanedioic acid
Molecular formula	C₁₅H₁₆BrN₅O₆
Molecular weight	442.22 g/mol
Exact mass	441.0284
Grade	IP/BP/USP
HSN code	2933
InChIKey	QZHBYNSSDLTCRG-LREBCSMRSA-N
SMILES	C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
PubChem CID	54405

Physical properties
Physical form	Powder
Appearance	White to slightly yellowish powder
H-bond donors / acceptors	6 / 9
TPSA	177 Å²
Synonyms	Brominide tartrate, Bromoxidine tartrate, Alphagan P, OCU-300, AGN-190342LF, 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline D-tartrate (1:1), Ratio Brimonidine, LUMIFY Redness Reliever Eye Drops, 5-bromo-6-(imidazolidinylideneamino)quinoxaline, Brimonidine Tartrate ophthalmic solution, 0.15%, 5-bromo-6-(2-imidazolin-2-ylamino)quinoxaline d-tartrate, 5-bromo-6-(imidazolin-2-ylamino)quinoxaline

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H331Toxic if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H371May cause damage to organs
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P233, P260, P261, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P308 + P316, P316, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P342 + P316

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 70359-46-5

Reference Standard

Brimonidine Tartrate

CAS: 70359-46-5
Formula: C₁₅H₁₆BrN₅O₆
MW: 442.22 g/mol

In stock

Frequently asked questions

What is the CAS number of Brimonidine?

The CAS Registry Number of Brimonidine is 70359-46-5. It is also known as Brominide tartrate, Bromoxidine tartrate, Alphagan P.

What is the molecular formula and molecular weight of Brimonidine?

Brimonidine has the molecular formula C15H16BrN5O6 and a molecular weight of 442.22 g/mol.

What is Brimonidine used for?

Brimonidine is supplied as a characterised reference material related to Brimonidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Brimonidine can I order?

We supply Brimonidine in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brimonidine?

Yes. Every lot of Brimonidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brimonidine be shipped internationally?

Yes. Brimonidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.