Clozapine EP Impurity C

Name: Clozapine EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-022250

About Clozapine EP Impurity C

Listed under CAS 6104-71-8, Clozapine EP Impurity C is a pharmacopeial impurity of Clozapine available from Vaqora Chemicals. The compound has the formula C17H17ClN4, corresponding to a molecular weight of 312.8 g/mol. Systematically, it is named 3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine. It is also known as Clozapine - Impurity C or N-Desmethylclozapine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Clozapine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Clozapine

View every impurity, metabolite and intermediate we list for Clozapine.

Clozapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Clozapine EP Impurity C
Catalogue No.	VQ-022250
CAS Number	6104-71-8
IUPAC name	3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine
Molecular formula	C₁₇H₁₇ClN₄
Molecular weight	312.8 g/mol
Exact mass	312.1142
Grade	Reference Standard
HSN code	38229090
InChIKey	JNNOSTQEZICQQP-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42
PubChem CID	135409468

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 3
TPSA	39.7 Å²
Synonyms	Clozapine - Impurity C, N-Desmethylclozapine, Norclozapine, Desmethylclozapine, 8-chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, 8-Chloro-11-(1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine, 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,E][1,4]diazepine, 8-chloro-11-piperazin-1-yl-5H-dibenzo(B,E)(1,4)diazepine, 8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine, 3-chloro-6-piperazin-1-yl-5H-benzo(c)(1,5)benzodiazepine, 3-chloro-6-piperazin-1-yl-5H-benzo[c][1,5]benzodiazepine, 8-chloro-11-(piperazin-1-yl)-5H-dibenzo(b,e)(1,4)diazepine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clozapine EP Impurity C?

The CAS Registry Number of Clozapine EP Impurity C is 6104-71-8. It is also known as Clozapine - Impurity C, N-Desmethylclozapine, Norclozapine.

What is the molecular formula and molecular weight of Clozapine EP Impurity C?

Clozapine EP Impurity C has the molecular formula C17H17ClN4 and a molecular weight of 312.8 g/mol. Its IUPAC name is 3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine.

What is Clozapine EP Impurity C used for?

Clozapine EP Impurity C is supplied as a characterised reference material related to Clozapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clozapine EP Impurity C can I order?

We supply Clozapine EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clozapine EP Impurity C?

Yes. Every lot of Clozapine EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clozapine EP Impurity C be shipped internationally?

Yes. Clozapine EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.