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VAQORACrizotinib
Synonyms: Xalkori · (R)-crizotinib · MET Tyrosine Kinase Inhibitor PF-02341066 · Crizotinib (PF-02341066)
CAS No.877399-52-5
FormulaC21H22Cl2FN5O
Mol. weight450.30
Catalogue No.VQ-007396
PurityReference Standard
HSN38229090
Crizotinib (CAS 877399-52-5) – Crizotinib reference standard. C21H22Cl2FN5O, MW 450.3. Supplied by Vaqora Chemicals with COA, exported worldwide.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
250 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Crizotinib
Vaqora Chemicals supplies Crizotinib, a high-purity reference standard of Crizotinib registered under CAS number 877399-52-5. The compound has the formula C21H22Cl2FN5O, corresponding to a molecular weight of 450.3 g/mol. Its systematic (IUPAC) name is 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine. Common synonyms include Xalkori and (R)-crizotinib.
The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
As a reference sample of Crizotinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Crizotinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- Identification & assay
- Method development & validation
- QC reference material
Industries
Related to Crizotinib
View every impurity, metabolite and intermediate we list for Crizotinib.
Crizotinib impuritiesSpecifications & identifiers
| Product name | Crizotinib |
|---|---|
| Catalogue No. | VQ-007396 |
| CAS Number | 877399-52-5 |
| IUPAC name | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine |
| Molecular formula | C21H22Cl2FN5O |
| Molecular weight | 450.3 g/mol |
| Exact mass | 449.1185 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | KTEIFNKAUNYNJU-GFCCVEGCSA-N |
| SMILES | C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N |
| PubChem CID | 11626560 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.7 |
| H-bond donors / acceptors | 2 / 6 |
| TPSA | 78 Ų |
| Synonyms | Xalkori, (R)-crizotinib, MET Tyrosine Kinase Inhibitor PF-02341066, Crizotinib (PF-02341066), Crizotinib (PF-2341066), C21H22Cl2FN5O, Xalkori (TN), 877399-52-5 (free base), Crizotinib (Standard), PF-2341066,Crizotinib, Crizotinib (JAN/USAN/INN), Crizotinib - Bio-X trade mark |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H317May cause an allergic skin reactionH318Causes serious eye damageH319Causes serious eye irritationH341Suspected of causing genetic defectsH400Very toxic to aquatic life
Precautionary statements: P203, P261, P264 + P265, P272, P273, P280, P302 + P352, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P321, P333 + P317, P337 + P317, P362 + P364, P391, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Crizotinib?
The CAS Registry Number of Crizotinib is 877399-52-5. It is also known as Xalkori, (R)-crizotinib, MET Tyrosine Kinase Inhibitor PF-02341066.
What is the molecular formula and molecular weight of Crizotinib?
Crizotinib has the molecular formula C21H22Cl2FN5O and a molecular weight of 450.3 g/mol. Its IUPAC name is 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine.
What is Crizotinib used for?
Crizotinib is supplied as a characterised reference material related to Crizotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Crizotinib can I order?
We supply Crizotinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Crizotinib?
Yes. Every lot of Crizotinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Crizotinib be shipped internationally?
Yes. Crizotinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Crizotinib
We reply within one business day with price, pack options, lead time and documentation.
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- CAS
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- Formula
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- Formula
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- CAS
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- Formula
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- MW
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- CAS
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- Formula
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- MW
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