Iso Cyclosporin A

Name: Iso Cyclosporin A
Brand: Vaqora Chemicals
SKU: VQ-025122

About Iso Cyclosporin A

Iso Cyclosporin A is an impurity of Cyclosporine carrying the CAS registry number 59865-16-6. Its molecular formula is C62H111N11O12 and its molecular weight is 1202.6 g/mol. It is also known as Cyclosporin A Isomer or Isociclosporin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Cyclosporine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Iso Cyclosporin A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cyclosporine

View every impurity, metabolite and intermediate we list for Cyclosporine.

Cyclosporine impurities

Specifications & identifiers

Chemical identifiers
Product name	Iso Cyclosporin A
Catalogue No.	VQ-025122
CAS Number	59865-16-6
IUPAC name	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S,34R)-30-ethyl-34-[(E,2R)-hex-4-en-2-yl]-4,7,10,12,15,19,25,28-octamethyl-33-(methylamino)-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1-oxa-4,7,10,13,16,19,22,25,28,31-decazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₂H₁₁₁N₁₁O₁₂
Molecular weight	1202.6 g/mol
Exact mass	1201.8414
Grade	Reference Standard
HSN code	38229090
InChIKey	QEKLELUAISGHEL-CGLBZJNRSA-N
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC)[C@H](C)C/C=C/C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
PubChem CID	101607771

Physical properties
Physical form	Solid
LogP (XLogP3)	7.6
H-bond donors / acceptors	5 / 13
TPSA	277 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Iso Cyclosporin A?

The CAS Registry Number of Iso Cyclosporin A is 59865-16-6. It is also known as Cyclosporin A Isomer, Isociclosporin.

What is the molecular formula and molecular weight of Iso Cyclosporin A?

Iso Cyclosporin A has the molecular formula C62H111N11O12 and a molecular weight of 1202.6 g/mol.

What is Iso Cyclosporin A used for?

Iso Cyclosporin A is supplied as a characterised reference material related to Cyclosporine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Iso Cyclosporin A can I order?

We supply Iso Cyclosporin A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Iso Cyclosporin A?

Yes. Every lot of Iso Cyclosporin A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Iso Cyclosporin A be shipped internationally?

Yes. Iso Cyclosporin A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.