Cyclosporin G

Name: Cyclosporin G
Brand: Vaqora Chemicals
SKU: VQ-025124

About Cyclosporin G

Cyclosporin G is an impurity of Cyclosporine carrying the CAS registry number 74436-00-3. With the molecular formula C63H113N11O12, it has a molar mass of 1216.6 g/mol. It is also known as Geclosporin or cyclosporine G.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Cyclosporine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Cyclosporin G in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cyclosporine

View every impurity, metabolite and intermediate we list for Cyclosporine.

Cyclosporine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclosporin G
Catalogue No.	VQ-025124
CAS Number	74436-00-3
IUPAC name	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₃H₁₁₃N₁₁O₁₂
Molecular weight	1216.6 g/mol
Exact mass	1215.857
Grade	Reference Standard
HSN code	38229090
InChIKey	ZMKGDQSIRSGUDJ-VSROPUKISA-N
SMILES	CCC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
PubChem CID	6475296

Physical properties
Physical form	Solid
LogP (XLogP3)	7.9
H-bond donors / acceptors	5 / 12
TPSA	279 Å²
Synonyms	Geclosporin, cyclosporine G, 2-norVal-cyclosporin, geclosporine, Cyclosporin A, 7-L-norvaline-, SDZ-37-325, NVa(2)-cyclosporin, 2-norvalyl-cyclosporin, norvaline(2)-cyclosporine, cyclosporin, 2-norvaline-, cyclosporin, norVal(2)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclosporin G?

The CAS Registry Number of Cyclosporin G is 74436-00-3. It is also known as Geclosporin, cyclosporine G, 2-norVal-cyclosporin.

What is the molecular formula and molecular weight of Cyclosporin G?

Cyclosporin G has the molecular formula C63H113N11O12 and a molecular weight of 1216.6 g/mol.

What is Cyclosporin G used for?

Cyclosporin G is supplied as a characterised reference material related to Cyclosporine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclosporin G can I order?

We supply Cyclosporin G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclosporin G?

Yes. Every lot of Cyclosporin G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclosporin G be shipped internationally?

Yes. We export Cyclosporin G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.