Cyclosporin C

Name: Cyclosporin C
Brand: Vaqora Chemicals
SKU: VQ-025119

About Cyclosporin C

Listed under CAS 59787-61-0, Cyclosporin C is an impurity of Cyclosporine available from Vaqora Chemicals. The compound has the formula C62H111N11O13, corresponding to a molecular weight of 1218.6 g/mol. Alternative names: 7-Threonine-cyclosporin A and Thr2-cyclosporine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Cyclosporine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cyclosporin C is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cyclosporine

View every impurity, metabolite and intermediate we list for Cyclosporine.

Cyclosporine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclosporin C
Catalogue No.	VQ-025119
CAS Number	59787-61-0
IUPAC name	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-[(1R)-1-hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₂H₁₁₁N₁₁O₁₃
Molecular weight	1218.6 g/mol
Exact mass	1217.8363
Grade	Reference Standard
HSN code	38229090
InChIKey	JTOKYIBTLUQVQV-QRVTZXGZSA-N
SMILES	C/C=C/C[C@@H](C)[C@H]([C@H]1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)[C@@H](C)O)O
PubChem CID	5287817

Physical properties
Physical form	Solid
LogP (XLogP3)	6.9
H-bond donors / acceptors	6 / 13
TPSA	299 Å²
Synonyms	7-Threonine-cyclosporin A, Thr2-cyclosporine, [Thr2]CsA, EX-A2529, Cyclosporin C(Discontinued,See C4X-19986), cyclo-[MeBmt-Thr-Sar-MeLeu-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal]

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclosporin C?

The CAS Registry Number of Cyclosporin C is 59787-61-0. It is also known as 7-Threonine-cyclosporin A, Thr2-cyclosporine, [Thr2]CsA.

What is the molecular formula and molecular weight of Cyclosporin C?

Cyclosporin C has the molecular formula C62H111N11O13 and a molecular weight of 1218.6 g/mol.

What is Cyclosporin C used for?

Cyclosporin C is supplied as a characterised reference material related to Cyclosporine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclosporin C can I order?

We supply Cyclosporin C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclosporin C?

Yes. Every lot of Cyclosporin C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclosporin C be shipped internationally?

Yes. Cyclosporin C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.