Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers)

Name: Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers)
Brand: Vaqora Chemicals
SKU: VQ-006828

About Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers)

Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) is a nitrosamine impurity of Osimertinib offered by Vaqora Chemicals with a typical assay of 22%. Formula C24H28N8O2, molecular weight 460.5 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Osimertinib, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers)
Catalogue No.	VQ-006828
IUPAC name	N-[2-[2-amino-5-methoxy-N-methyl-4-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]anilino]ethyl]-N-methylnitrous amide
Molecular formula	C₂₄H₂₈N₈O₂
Molecular weight	460.5 g/mol
Exact mass	460.2335
Grade	Reference Standard
Purity / assay	22%
HSN code	38229090
InChIKey	UIKFMOIBBHKVFQ-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)N=O)OC
PubChem CID	177807286

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 9
TPSA	114 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the molecular formula and molecular weight of Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers)?

Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) has the molecular formula C24H28N8O2 and a molecular weight of 460.5 g/mol. Its IUPAC name is N-[2-[2-amino-5-methoxy-N-methyl-4-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]anilino]ethyl]-N-methylnitrous amide.

What is Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) used for?

Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) can I order?

We supply Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) in Reference Standard (22%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers)?

Yes. Every lot of Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) be shipped internationally?

Yes. We export Des Acryl Des Methyl N-Nitroso Osimertinib (Rotamers) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.