Osimertinib N'-Oxide Impurity

Name: Osimertinib N'-Oxide Impurity
Brand: Vaqora Chemicals
SKU: VQ-005449

About Osimertinib N'-Oxide Impurity

Osimertinib N'-Oxide Impurity (CAS 1975982-94-5) is an impurity of Osimertinib offered by Vaqora Chemicals at a purity of 95.07%. With the molecular formula C28H33N7O3, it has a molar mass of 515.6 g/mol. Alternative names: Osimertinib N'-Oxide and Osimertinib Impurity M.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Osimertinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Osimertinib N'-Oxide Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Osimertinib N'-Oxide Impurity
Catalogue No.	VQ-005449
CAS Number	1975982-94-5
IUPAC name	2-[5-methoxy-N-methyl-4-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-(prop-2-enoylamino)anilino]-N,N-dimethylethanamine oxide
Molecular formula	C₂₈H₃₃N₇O₃
Molecular weight	515.6 g/mol
Exact mass	515.2645
Grade	Reference Standard
Purity / assay	95.07%
HSN code	38229090
InChIKey	LOBAQJFXRBFPOQ-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CC[N+](C)(C)[O-])OC
PubChem CID	132609257

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 7
TPSA	102 Å²
Synonyms	Osimertinib N'-Oxide, Osimertinib Impurity M, Osimertinib Impurity 1, Osimertinib metabolite M1, AZD-9291 Impurity 14, OsimertinibN inverted exclamation mark -Oxide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Osimertinib N'-Oxide Impurity?

The CAS Registry Number of Osimertinib N'-Oxide Impurity is 1975982-94-5. It is also known as Osimertinib N'-Oxide, Osimertinib Impurity M, Osimertinib Impurity 1.

What is the molecular formula and molecular weight of Osimertinib N'-Oxide Impurity?

Osimertinib N'-Oxide Impurity has the molecular formula C28H33N7O3 and a molecular weight of 515.6 g/mol. Its IUPAC name is 2-[5-methoxy-N-methyl-4-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-(prop-2-enoylamino)anilino]-N,N-dimethylethanamine oxide.

What is Osimertinib N'-Oxide Impurity used for?

Osimertinib N'-Oxide Impurity is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Osimertinib N'-Oxide Impurity can I order?

We supply Osimertinib N'-Oxide Impurity in Reference Standard (95.07%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Osimertinib N'-Oxide Impurity?

Yes. Every lot of Osimertinib N'-Oxide Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Osimertinib N'-Oxide Impurity be shipped internationally?

Yes. We export Osimertinib N'-Oxide Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.