Desacrylamide Nitro Osimertinib

Name: Desacrylamide Nitro Osimertinib
Brand: Vaqora Chemicals
SKU: VQ-004756

About Desacrylamide Nitro Osimertinib

Desacrylamide Nitro Osimertinib (CAS 1421372-67-9) is an impurity of Osimertinib offered by Vaqora Chemicals. Formula C25H29N7O3, molecular weight 475.5 g/mol. Alternative names: Desacryloyl Osimertinib and AZD9291 Intermediate 3.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Osimertinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Desacrylamide Nitro Osimertinib
Catalogue No.	VQ-004756
CAS Number	1421372-67-9
IUPAC name	4-N-[2-(dimethylamino)ethyl]-2-methoxy-4-N-methyl-1-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]-5-nitrobenzene-1,4-diamine
Molecular formula	C₂₅H₂₉N₇O₃
Molecular weight	475.5 g/mol
Exact mass	475.2332
Grade	Reference Standard
HSN code	38229090
InChIKey	PKEPAQKEINNCAB-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=CC(=C(C=C4OC)N(C)CCN(C)C)[N+](=O)[O-]
PubChem CID	71239349

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 8
TPSA	104 Å²
Synonyms	Desacryloyl Osimertinib, AZD9291 Intermediate 3, AZD 9291 Intermediate 3, CS-M2845, 1,4-Benzenediamine, N1-[2-(dimethylamino)ethyl]-5-methoxy-N1-methyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Desacrylamide Nitro Osimertinib?

The CAS Registry Number of Desacrylamide Nitro Osimertinib is 1421372-67-9. It is also known as Desacryloyl Osimertinib, AZD9291 Intermediate 3, AZD 9291 Intermediate 3.

What is the molecular formula and molecular weight of Desacrylamide Nitro Osimertinib?

Desacrylamide Nitro Osimertinib has the molecular formula C25H29N7O3 and a molecular weight of 475.5 g/mol. Its IUPAC name is 4-N-[2-(dimethylamino)ethyl]-2-methoxy-4-N-methyl-1-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]-5-nitrobenzene-1,4-diamine.

What is Desacrylamide Nitro Osimertinib used for?

Desacrylamide Nitro Osimertinib is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Desacrylamide Nitro Osimertinib can I order?

We supply Desacrylamide Nitro Osimertinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Desacrylamide Nitro Osimertinib?

Yes. Every lot of Desacrylamide Nitro Osimertinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Desacrylamide Nitro Osimertinib be shipped internationally?

Yes. We export Desacrylamide Nitro Osimertinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.