Osimertinib Impurity G

Name: Osimertinib Impurity G
Brand: Vaqora Chemicals
SKU: VQ-005446

About Osimertinib Impurity G

Listed under CAS 2044702-39-6, Osimertinib Impurity G is an impurity of Osimertinib available from Vaqora Chemicals, specified at 98.67% purity. Its molecular formula is C25H26N6O2 and its molecular weight is 442.5 g/mol. Systematically, it is named N-[2-(dimethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide. Alternative names: Osimertinib Impurity 5 and N-Desdimethylaminoethyl-N-methyl Osimertinib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Osimertinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg and 25 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Osimertinib Impurity G
Catalogue No.	VQ-005446
CAS Number	2044702-39-6
IUPAC name	N-[2-(dimethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
Molecular formula	C₂₅H₂₆N₆O₂
Molecular weight	442.5 g/mol
Exact mass	442.2117
Grade	Reference Standard
Purity / assay	98.67%
HSN code	38229090
InChIKey	HRUWUYCHGAPMSO-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)C)OC
PubChem CID	127255561

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 6
TPSA	84.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Osimertinib Impurity G?

The CAS Registry Number of Osimertinib Impurity G is 2044702-39-6. It is also known as Osimertinib Impurity 5, N-Desdimethylaminoethyl-N-methyl Osimertinib, AZD-9291 Impurity 7.

What is the molecular formula and molecular weight of Osimertinib Impurity G?

Osimertinib Impurity G has the molecular formula C25H26N6O2 and a molecular weight of 442.5 g/mol. Its IUPAC name is N-[2-(dimethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide.

What is Osimertinib Impurity G used for?

Osimertinib Impurity G is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Osimertinib Impurity G can I order?

We supply Osimertinib Impurity G in Reference Standard (98.67%) grade, in 10 mg, 25 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Osimertinib Impurity G?

Yes. Every lot of Osimertinib Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Osimertinib Impurity G be shipped internationally?

Yes. We export Osimertinib Impurity G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.