Osimertinib Amine Impurity

Name: Osimertinib Amine Impurity
Brand: Vaqora Chemicals
SKU: VQ-005441

About Osimertinib Amine Impurity

Listed under CAS 1421372-66-8, Osimertinib Amine Impurity is an impurity of Osimertinib available from Vaqora Chemicals. Its molecular formula is C25H31N7O and its molecular weight is 445.6 g/mol. It is also known as AZD 9291DA or Osimertinib DP-2 Impurity.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Osimertinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Osimertinib Amine Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Osimertinib Amine Impurity
Catalogue No.	VQ-005441
CAS Number	1421372-66-8
IUPAC name	1-N-[2-(dimethylamino)ethyl]-5-methoxy-1-N-methyl-4-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine
Molecular formula	C₂₅H₃₁N₇O
Molecular weight	445.6 g/mol
Exact mass	445.259
Grade	Reference Standard
HSN code	38229090
InChIKey	HTNTZPBKKCORTP-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)C)OC
PubChem CID	78358313

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	2 / 7
TPSA	84.5 Å²
Synonyms	AZD 9291DA, Osimertinib DP-2 Impurity, Mutated EGFR-IN-1, AZD9291DA HCl salt, Osimertinib Impurity 11, MutatedEGFR-IN-1, Mutated EGFR-IN-1(Osimertinib analog)?

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Osimertinib Amine Impurity?

The CAS Registry Number of Osimertinib Amine Impurity is 1421372-66-8. It is also known as AZD 9291DA, Osimertinib DP-2 Impurity, Mutated EGFR-IN-1.

What is the molecular formula and molecular weight of Osimertinib Amine Impurity?

Osimertinib Amine Impurity has the molecular formula C25H31N7O and a molecular weight of 445.6 g/mol. Its IUPAC name is 1-N-[2-(dimethylamino)ethyl]-5-methoxy-1-N-methyl-4-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine.

What is Osimertinib Amine Impurity used for?

Osimertinib Amine Impurity is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Osimertinib Amine Impurity can I order?

We supply Osimertinib Amine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Osimertinib Amine Impurity?

Yes. Every lot of Osimertinib Amine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Osimertinib Amine Impurity be shipped internationally?

Yes. We export Osimertinib Amine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.