Despropylaminosulfonyl Macitentan

Name: Despropylaminosulfonyl Macitentan
Brand: Vaqora Chemicals
SKU: VQ-021266

About Despropylaminosulfonyl Macitentan

Listed under CAS 1433875-21-8, Despropylaminosulfonyl Macitentan is a metabolite or degradation product of Macitentan available from Vaqora Chemicals. With the molecular formula C16H13Br2N5O2, it has a molar mass of 467.1 g/mol. Systematically, it is named 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-amine. Common synonyms include Macitentan Amine and Macitentan metabolite M3.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Macitentan, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Despropylaminosulfonyl Macitentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Despropylaminosulfonyl Macitentan
Catalogue No.	VQ-021266
CAS Number	1433875-21-8
IUPAC name	5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-amine
Molecular formula	C₁₆H₁₃Br₂N₅O₂
Molecular weight	467.1 g/mol
Exact mass	466.9416
Grade	Reference Standard
HSN code	38229090
InChIKey	LFEPQTGGEXKQEY-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)N)Br
PubChem CID	67041378

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	1 / 7
TPSA	96 Å²
Synonyms	Macitentan Amine, Macitentan metabolite M3, 4-Pyrimidinamine, 5-(4-bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-, 5-(4-Bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinamine, 5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinamine, 4-Pyrimidinamine, 5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-, 5-(4-bromophenyl)-6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)pyrimidin-4-amine, 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-amine, CS-M2652, 5-(4-Bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-ylamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Despropylaminosulfonyl Macitentan?

The CAS Registry Number of Despropylaminosulfonyl Macitentan is 1433875-21-8. It is also known as Macitentan Amine, Macitentan metabolite M3, 4-Pyrimidinamine, 5-(4-bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-.

What is the molecular formula and molecular weight of Despropylaminosulfonyl Macitentan?

Despropylaminosulfonyl Macitentan has the molecular formula C16H13Br2N5O2 and a molecular weight of 467.1 g/mol. Its IUPAC name is 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-amine.

What is Despropylaminosulfonyl Macitentan used for?

Despropylaminosulfonyl Macitentan is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Despropylaminosulfonyl Macitentan can I order?

We supply Despropylaminosulfonyl Macitentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Despropylaminosulfonyl Macitentan?

Yes. Every lot of Despropylaminosulfonyl Macitentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Despropylaminosulfonyl Macitentan be shipped internationally?

Yes. We export Despropylaminosulfonyl Macitentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.