O-Desbromo-Pyrimidinyl Macitentan

Name: O-Desbromo-Pyrimidinyl Macitentan
Brand: Vaqora Chemicals
SKU: VQ-021264

About O-Desbromo-Pyrimidinyl Macitentan

Vaqora Chemicals supplies O-Desbromo-Pyrimidinyl Macitentan, a metabolite or degradation product of Macitentan registered under CAS number 1393813-43-8. The compound has the formula C15H19BrN4O4S, corresponding to a molecular weight of 431.3 g/mol. The IUPAC name is 2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyethanol. Common synonyms include Macitentan metabolite M4 and CS-M1796.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Macitentan, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies O-Desbromo-Pyrimidinyl Macitentan in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desbromo-Pyrimidinyl Macitentan
Catalogue No.	VQ-021264
CAS Number	1393813-43-8
IUPAC name	2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyethanol
Molecular formula	C₁₅H₁₉BrN₄O₄S
Molecular weight	431.3 g/mol
Exact mass	430.031
Grade	Reference Standard
HSN code	38229090
InChIKey	MKPBJHFHEQSWAH-UHFFFAOYSA-N
SMILES	CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCO)C2=CC=C(C=C2)Br
PubChem CID	70813943

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	3 / 8
TPSA	122 Å²
Synonyms	N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide, Macitentan metabolite M4, N-[5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-N'-propylsulfamide, N-(5-(4-Bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl)-N'-propylsulfamide, N-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide, Sulfamide, N-[5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-N'-propyl-, N-5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl-N'-propylsulfamide, 2-{[5-(4-bromophenyl)-6-[(propylsulfamoyl)amino]pyrimidin-4-yl]oxy}ethan-1-ol, Sulfamide, N-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl)-N'-propyl-, CS-M1796, n-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl)-n'-p...

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desbromo-Pyrimidinyl Macitentan?

The CAS Registry Number of O-Desbromo-Pyrimidinyl Macitentan is 1393813-43-8. It is also known as N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide, Macitentan metabolite M4, N-[5-(4-bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-N'-propylsulfamide.

What is the molecular formula and molecular weight of O-Desbromo-Pyrimidinyl Macitentan?

O-Desbromo-Pyrimidinyl Macitentan has the molecular formula C15H19BrN4O4S and a molecular weight of 431.3 g/mol. Its IUPAC name is 2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyethanol.

What is O-Desbromo-Pyrimidinyl Macitentan used for?

O-Desbromo-Pyrimidinyl Macitentan is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desbromo-Pyrimidinyl Macitentan can I order?

We supply O-Desbromo-Pyrimidinyl Macitentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desbromo-Pyrimidinyl Macitentan?

Yes. Every lot of O-Desbromo-Pyrimidinyl Macitentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desbromo-Pyrimidinyl Macitentan be shipped internationally?

Yes. We export O-Desbromo-Pyrimidinyl Macitentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.