Diltiazem EP Impurity D

Name: Diltiazem EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-006330

About Diltiazem EP Impurity D

Diltiazem EP Impurity D (CAS 130606-60-9) is a pharmacopeial impurity of Diltiazem offered by Vaqora Chemicals, specified at 98.99% purity. Formula C21H25ClN2O4S, molecular weight 437.0 g/mol. Common synonyms include N-Desmethyl Diltiazem Hydrochloride and N-Demethyldiltiazem hydrochloride.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Diltiazem impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Diltiazem EP Impurity D is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diltiazem EP Impurity D
Catalogue No.	VQ-006330
CAS Number	130606-60-9
Other CAS	86408-45-9
IUPAC name	[(2S,3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride
Molecular formula	C₂₁H₂₅ClN₂O₄S
Molecular weight	437 g/mol
Exact mass	436.1224
Grade	Reference Standard
Purity / assay	98.99%
HSN code	38229090
InChIKey	GIYQYIVUHPJUHS-FDOHDBATSA-N
SMILES	CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCNC)C3=CC=C(C=C3)OC.Cl
PubChem CID	14391644

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 6
TPSA	93.2 Å²
Synonyms	N-Desmethyl Diltiazem Hydrochloride, N-Demethyldiltiazem hydrochloride, N-Demethyl diltiazem hydrochloride, N-desmethyl Diltiazem (hydrochloride), Diltiazem Impurity D (N-Desmethyl diltiazem HCl), Diltiazem N-desmethyl hydrochloride, Diltiazem Impurity, Diltiazem EP Impurity D HCl, Diltiazem N-desmethyl hydrochloride 100 microg/mL in Acetonitrile, N-Desmethyldiltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diltiazem EP Impurity D?

The CAS Registry Number of Diltiazem EP Impurity D is 130606-60-9. It is also known as N-Desmethyl Diltiazem Hydrochloride, N-Demethyldiltiazem hydrochloride, N-Demethyl diltiazem hydrochloride.

What is the molecular formula and molecular weight of Diltiazem EP Impurity D?

Diltiazem EP Impurity D has the molecular formula C21H25ClN2O4S and a molecular weight of 437 g/mol.

What is Diltiazem EP Impurity D used for?

Diltiazem EP Impurity D is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diltiazem EP Impurity D can I order?

We supply Diltiazem EP Impurity D in Reference Standard (98.99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diltiazem EP Impurity D?

Yes. Every lot of Diltiazem EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diltiazem EP Impurity D be shipped internationally?

Yes. Diltiazem EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.