Diltiazem EP Impurity D (Freebase)

Name: Diltiazem EP Impurity D (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006331

About Diltiazem EP Impurity D (Freebase)

Diltiazem EP Impurity D (Freebase) is a pharmacopeial impurity of Diltiazem carrying the CAS registry number 86408-45-9. Formula C21H24N2O4S, molecular weight 400.5 g/mol. The IUPAC name is [(2S,3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Common synonyms include N-Monodesmethyldiltiazem and N-Desmethyl Diltiazem.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Diltiazem, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Diltiazem EP Impurity D (Freebase) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diltiazem EP Impurity D (Freebase)
Catalogue No.	VQ-006331
CAS Number	86408-45-9
Other CAS	130606-60-9
IUPAC name	[(2S,3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
Molecular formula	C₂₁H₂₄N₂O₄S
Molecular weight	400.5 g/mol
Exact mass	400.1457
Grade	Reference Standard
HSN code	38229090
InChIKey	YOMLDISQSWWYOT-UXHICEINSA-N
SMILES	CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCNC)C3=CC=C(C=C3)OC
PubChem CID	107891

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 6
TPSA	93.2 Å²
Synonyms	N-Monodesmethyldiltiazem, N-Desmethyl Diltiazem, Diltiazem EP Impurity D(Freebase), N-Demethyldiltiazem, N-Desmethyldiltiazem, N-Monodemethyldiltiazem, Diltiazem Impurity, desmethyl diltiazem

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diltiazem EP Impurity D (Freebase)?

The CAS Registry Number of Diltiazem EP Impurity D (Freebase) is 86408-45-9. It is also known as N-Monodesmethyldiltiazem, N-Desmethyl Diltiazem, Diltiazem EP Impurity D(Freebase).

What is the molecular formula and molecular weight of Diltiazem EP Impurity D (Freebase)?

Diltiazem EP Impurity D (Freebase) has the molecular formula C21H24N2O4S and a molecular weight of 400.5 g/mol. Its IUPAC name is [(2S,3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate.

What is Diltiazem EP Impurity D (Freebase) used for?

Diltiazem EP Impurity D (Freebase) is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diltiazem EP Impurity D (Freebase) can I order?

We supply Diltiazem EP Impurity D (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diltiazem EP Impurity D (Freebase)?

Yes. Every lot of Diltiazem EP Impurity D (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diltiazem EP Impurity D (Freebase) be shipped internationally?

Yes. We export Diltiazem EP Impurity D (Freebase) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.