Doxazosin EP Impurity B

Name: Doxazosin EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022442

About Doxazosin EP Impurity B

Doxazosin EP Impurity B (CAS 70918-74-0) is a pharmacopeial impurity of Doxazosin offered by Vaqora Chemicals. Formula C13H17ClN2O3, molecular weight 284.74 g/mol. It is also known as Doxazosin EP Impurity B Hydrochloride or Doxazosin Mesylate - Impurity B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

This Doxazosin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Doxazosin

View every impurity, metabolite and intermediate we list for Doxazosin.

Doxazosin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Doxazosin EP Impurity B
Catalogue No.	VQ-022442
CAS Number	70918-74-0
IUPAC name	2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone;hydrochloride
Molecular formula	C₁₃H₁₇ClN₂O₃
Molecular weight	284.74 g/mol
Exact mass	284.0928
Grade	Reference Standard
HSN code	38229090
InChIKey	TUKBWYXLYINULI-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C(=O)C2COC3=CC=CC=C3O2.Cl
PubChem CID	2822434

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	50.8 Å²
Synonyms	Doxazosin EP Impurity B Hydrochloride, Doxazosin Mesylate - Impurity B, 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride, Methanone, (2,3-dihydro-1,4-benzodioxin-2-yl)-1-piperazinyl-, hydrochloride (1:1), 1-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride, 2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride, N-(1,4-Benzodioxan-2-Carbonyl)Piperazine Hydrochloride, (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone hydrochloride, n-(1,4-benzodioxan-2-carbonyl)-piperazine hydrochloride, (2,3-Dihydrobenzo[1,4]dioxin-2-yl)piperazin-1-yl-methanone hydrochloride, 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride, 1-[(2RS)-2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl]piperazine Hydrochloride

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P262, P264, P270, P271, P273, P280, P301 + P316, P302 + P352, P304 + P340, P316, P319, P321, P330, P361 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxazosin EP Impurity B?

The CAS Registry Number of Doxazosin EP Impurity B is 70918-74-0. It is also known as Doxazosin EP Impurity B Hydrochloride, Doxazosin Mesylate - Impurity B, 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride.

What is the molecular formula and molecular weight of Doxazosin EP Impurity B?

Doxazosin EP Impurity B has the molecular formula C13H17ClN2O3 and a molecular weight of 284.74 g/mol.

What is Doxazosin EP Impurity B used for?

Doxazosin EP Impurity B is supplied as a characterised reference material related to Doxazosin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxazosin EP Impurity B can I order?

We supply Doxazosin EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxazosin EP Impurity B?

Yes. Every lot of Doxazosin EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxazosin EP Impurity B be shipped internationally?

Yes. Doxazosin EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.