Terazosin EP Impurity E

Name: Terazosin EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022441

About Terazosin EP Impurity E

Terazosin EP Impurity E is a pharmacopeial impurity of Doxazosin carrying the CAS registry number 102839-00-9. Its molecular formula is C24H28N8O4 and its molecular weight is 492.5 g/mol. Systematically, it is named 2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine. Alternative names: Prazosin EP Impurity E and Doxazosin EP Impurity H.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Doxazosin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Doxazosin

View every impurity, metabolite and intermediate we list for Doxazosin.

Doxazosin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Terazosin EP Impurity E
Catalogue No.	VQ-022441
CAS Number	102839-00-9
IUPAC name	2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Molecular formula	C₂₄H₂₈N₈O₄
Molecular weight	492.5 g/mol
Exact mass	492.2234
Grade	Reference Standard
HSN code	38229090
InChIKey	XJWKWPCORQUMQI-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C4=NC5=CC(=C(C=C5C(=N4)N)OC)OC)N)OC
PubChem CID	616293

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 12
TPSA	147 Å²
Synonyms	Prazosin EP Impurity E, Doxazosin EP Impurity H, Terazosin EP Impurity E (free base), Prazosin Hydrochloride - Impurity E, Terazosin Hydrochloride Dihydrate - Impurity E, Doxazosin Mesylate - Impurity H (FREE BASE), Doxazosin impurity H, 2,2'-(Piperazine-1,4-diyl)bis(6,7-dimethoxyquinazolin-4-amine), 1,4-Bis(4-amino-6,7-dimethoxy-2-quinazolinyl)piperazine, Doxazosin mesilate impurity H, 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine]

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Terazosin EP Impurity E?

The CAS Registry Number of Terazosin EP Impurity E is 102839-00-9. It is also known as Prazosin EP Impurity E, Doxazosin EP Impurity H, Terazosin EP Impurity E (free base).

What is the molecular formula and molecular weight of Terazosin EP Impurity E?

Terazosin EP Impurity E has the molecular formula C24H28N8O4 and a molecular weight of 492.5 g/mol. Its IUPAC name is 2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine.

What is Terazosin EP Impurity E used for?

Terazosin EP Impurity E is supplied as a characterised reference material related to Doxazosin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Terazosin EP Impurity E can I order?

We supply Terazosin EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Terazosin EP Impurity E?

Yes. Every lot of Terazosin EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Terazosin EP Impurity E be shipped internationally?

Yes. Terazosin EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.