Entacapone EP Impurity G

Name: Entacapone EP Impurity G
Brand: Vaqora Chemicals
SKU: VQ-022533

About Entacapone EP Impurity G

Entacapone EP Impurity G is a pharmacopeial impurity of Entacapone carrying the CAS registry number 1364322-41-7. The compound has the formula C11H9N3O5, corresponding to a molecular weight of 263.21 g/mol. Systematically, it is named (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide. It is also known as Entacapone - Impurity G or Entacapone impurity G.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Entacapone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entacapone EP Impurity G
Catalogue No.	VQ-022533
CAS Number	1364322-41-7
IUPAC name	(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide
Molecular formula	C₁₁H₉N₃O₅
Molecular weight	263.21 g/mol
Exact mass	263.0542
Grade	Reference Standard
HSN code	38229090
InChIKey	PJVWDBNDLNEXCN-FARCUNLSSA-N
SMILES	CNC(=O)/C(=C/C1=CC(=C(C(=C1)O)O)[N+](=O)[O-])/C#N
PubChem CID	71587989

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	3 / 6
TPSA	139 Å²
Synonyms	Entacapone - Impurity G, (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide, 2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide, (2E)-, 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-, (2E)-, Entacapone impurity G, (E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylacrylamide, (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-prop-2-enamide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Entacapone EP Impurity G?

The CAS Registry Number of Entacapone EP Impurity G is 1364322-41-7. It is also known as Entacapone - Impurity G, (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide, 2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide, (2E)-.

What is the molecular formula and molecular weight of Entacapone EP Impurity G?

Entacapone EP Impurity G has the molecular formula C11H9N3O5 and a molecular weight of 263.21 g/mol. Its IUPAC name is (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylprop-2-enamide.

What is Entacapone EP Impurity G used for?

Entacapone EP Impurity G is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entacapone EP Impurity G can I order?

We supply Entacapone EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entacapone EP Impurity G?

Yes. Every lot of Entacapone EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entacapone EP Impurity G be shipped internationally?

Yes. Entacapone EP Impurity G is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.