Entacapone EP Impurity H

Name: Entacapone EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-022534

About Entacapone EP Impurity H

Entacapone EP Impurity H (CAS 1150310-15-8) is a pharmacopeial impurity of Entacapone offered by Vaqora Chemicals. The compound has the formula C15H15N3O5, corresponding to a molecular weight of 317.3 g/mol. Systematically, it is named (E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile. Common synonyms include Entacapone - Impurity H and Entacapone impurity H.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Entacapone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Entacapone EP Impurity H in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entacapone EP Impurity H
Catalogue No.	VQ-022534
CAS Number	1150310-15-8
IUPAC name	(E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile
Molecular formula	C₁₅H₁₅N₃O₅
Molecular weight	317.3 g/mol
Exact mass	317.1012
Grade	Reference Standard
HSN code	38229090
InChIKey	NVHDZUJODMCISU-IZZDOVSWSA-N
SMILES	C1CCN(CC1)C(=O)/C(=C/C2=CC(=C(C(=C2)O)O)[N+](=O)[O-])/C#N
PubChem CID	44592489

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 6
TPSA	130 Å²
Synonyms	Entacapone - Impurity H, (2E)-3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidin-1-ylcarbonyl)prop-2-ennitrile, 3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidin-1-ylcarbonyl)prop-2-ennitrile, (2E)-, Entacapone impurity H, (E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)acrylonitrile, (2E)-3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Entacapone EP Impurity H?

The CAS Registry Number of Entacapone EP Impurity H is 1150310-15-8. It is also known as Entacapone - Impurity H, (2E)-3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidin-1-ylcarbonyl)prop-2-ennitrile, 3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidin-1-ylcarbonyl)prop-2-ennitrile, (2E)-.

What is the molecular formula and molecular weight of Entacapone EP Impurity H?

Entacapone EP Impurity H has the molecular formula C15H15N3O5 and a molecular weight of 317.3 g/mol. Its IUPAC name is (E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile.

What is Entacapone EP Impurity H used for?

Entacapone EP Impurity H is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entacapone EP Impurity H can I order?

We supply Entacapone EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entacapone EP Impurity H?

Yes. Every lot of Entacapone EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entacapone EP Impurity H be shipped internationally?

Yes. Entacapone EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.