Ezetimibe

Name: Ezetimibe
Brand: Vaqora Chemicals
SKU: VQ-004090

About Ezetimibe

Vaqora Chemicals supplies Ezetimibe (IP/BP/USP grade), a cardiovascular API registered under CAS number 163222-33-1, specified at ≥99.0% purity. Formula C24H21F2NO3, molecular weight 409.4 g/mol. Systematically, it is named (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one. It is also known as Ezetrol or Ezetimibe (Standard).

The material typically appears as a white solid. Keep the container tightly sealed and store it in a cool, dry area. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As an active pharmaceutical ingredient within our cardiovascular and antihypertensive APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Enzyme inhibition studies
Pharmaceutical formulation

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ezetimibe
Catalogue No.	VQ-004090
CAS Number	163222-33-1
IUPAC name	(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Molecular formula	C₂₄H₂₁F₂NO₃
Molecular weight	409.4 g/mol
Exact mass	409.1489
Grade	IP/BP/USP
Purity / assay	≥99.0%
HSN code	2933
InChIKey	OLNTVTPDXPETLC-XPWALMASSA-N
SMILES	C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
PubChem CID	150311

Physical properties
Physical form	Solid
Appearance	White solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 5
TPSA	60.8 Å²
Synonyms	Ezetrol, Ezetimibe (Standard), Ezetimibe (JAN/USP/INN), Zetia (TN), Ezetimibe), ezetimibe anhydrate, Ezetimibe (Zetia)?, Ezetimibe - Bio-X trade mark, Ezetimibe, >=98% (HPLC), EX-A795, Ezetimibe, United States Pharmacopeia (USP) Reference Standard, Ezetimibe, Pharmaceutical Secondary Standard

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 163222-33-1

Reference Standard

Ezetimibe

CAS: 163222-33-1
Formula: C₂₄H₂₁F₂NO₃
MW: 409.4 g/mol

In stock

Frequently asked questions

What is the CAS number of Ezetimibe?

The CAS Registry Number of Ezetimibe is 163222-33-1. It is also known as Ezetrol, Ezetimibe (Standard), Ezetimibe (JAN/USP/INN).

What is the molecular formula and molecular weight of Ezetimibe?

Ezetimibe has the molecular formula C24H21F2NO3 and a molecular weight of 409.4 g/mol. Its IUPAC name is (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one.

What is Ezetimibe used for?

Ezetimibe is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ezetimibe can I order?

We supply Ezetimibe in IP/BP/USP (≥99.0%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ezetimibe?

Yes. Every lot of Ezetimibe is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ezetimibe be shipped internationally?

Yes. Ezetimibe is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.