Febuxostat

Name: Febuxostat
Brand: Vaqora Chemicals
SKU: VQ-004128

About Febuxostat

Febuxostat is a metabolic / hormonal API (IP/BP/USP grade) carrying the CAS registry number 144060-53-7 at a purity of ≥98.5%. Formula C16H16N2O3S, molecular weight 316.4 g/mol. Its systematic (IUPAC) name is 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid. Common synonyms include Adenuric and Uloric.

In its supplied form it is a white to yellow crystalline powder(Results:White crystalline powder). Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our antidiabetic, hormone and metabolic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Typical end-use sectors are pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Febuxostat is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Febuxostat

View every impurity, metabolite and intermediate we list for Febuxostat.

Febuxostat impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Febuxostat
Catalogue No.	VQ-004128
CAS Number	144060-53-7
IUPAC name	2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Molecular formula	C₁₆H₁₆N₂O₃S
Molecular weight	316.4 g/mol
Exact mass	316.0882
Grade	IP/BP/USP
Purity / assay	≥98.5%
HSN code	2933
InChIKey	BQSJTQLCZDPROO-UHFFFAOYSA-N
SMILES	CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O
PubChem CID	134018

Physical properties
Physical form	Powder
Appearance	White to yellow crystalline powder(Results:White crystalline powder)
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 6
TPSA	111 Å²
Synonyms	Adenuric, Uloric, TMX-67, Tei 6720, Tei-6720, TMX 67, 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid, 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-1,3-thiazole-5-carboxylic acid, 6720, TEI, Febuxostat tablets 40 mg, Febuxostat tablets 80 mg

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P263, P264, P270, P273, P301 + P317, P318, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 144060-53-7

Reference Standard

Febuxostat

CAS: 144060-53-7
Formula: C₁₆H₁₆N₂O₃S
MW: 316.4 g/mol

VQ-007475

Frequently asked questions

What is the CAS number of Febuxostat?

The CAS Registry Number of Febuxostat is 144060-53-7. It is also known as Adenuric, Uloric, TMX-67.

What is the molecular formula and molecular weight of Febuxostat?

Febuxostat has the molecular formula C16H16N2O3S and a molecular weight of 316.4 g/mol. Its IUPAC name is 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid.

What is Febuxostat used for?

Febuxostat is supplied as a characterised reference material related to Febuxostat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Febuxostat can I order?

We supply Febuxostat in IP/BP/USP (≥98.5%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Febuxostat?

Yes. Every lot of Febuxostat is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Febuxostat be shipped internationally?

Yes. Febuxostat is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.