Hydroxybupropion

Name: Hydroxybupropion
Brand: Vaqora Chemicals
SKU: VQ-021920

About Hydroxybupropion

Vaqora Chemicals supplies Hydroxybupropion, a metabolite or degradation product of Bupropion registered under CAS number 92264-81-8. With the molecular formula C13H18ClNO2, it has a molar mass of 255.74 g/mol. Its systematic (IUPAC) name is 1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one. Alternative names: 4-Hydroxy bupropion and 6-Hydroxybupropion.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bupropion, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Hydroxybupropion in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxybupropion
Catalogue No.	VQ-021920
CAS Number	92264-81-8
IUPAC name	1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one
Molecular formula	C₁₃H₁₈ClNO₂
Molecular weight	255.74 g/mol
Exact mass	255.1026
Grade	Reference Standard
HSN code	38229090
InChIKey	AKOAEVOSDHIVFX-UHFFFAOYSA-N
SMILES	CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)CO
PubChem CID	446

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 3
TPSA	49.3 Å²
Synonyms	4-Hydroxy bupropion, 6-Hydroxybupropion, BW-306U, 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 1-(3-chlorophenyl)-2-((1-hydroxy-2-methylpropan-2-yl)amino)propan-1-one, 1-Propanone, 1-(3-chlorophenyl)-2-((2-hydroxy-1,1-dimethylethyl)amino)-, US9333197, Hydroxybupropion, 2-(1-hydroxy-2-methylpropan-2-ylamino)-1-(3-chlorophenyl)propan-1-one, 1-(3-chlorophenyl)-2-[(2-methyl-1-oxidanyl-propan-2-yl)amino]propan-1-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxybupropion?

The CAS Registry Number of Hydroxybupropion is 92264-81-8. It is also known as 4-Hydroxy bupropion, 6-Hydroxybupropion, BW-306U.

What is the molecular formula and molecular weight of Hydroxybupropion?

Hydroxybupropion has the molecular formula C13H18ClNO2 and a molecular weight of 255.74 g/mol. Its IUPAC name is 1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one.

What is Hydroxybupropion used for?

Hydroxybupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxybupropion can I order?

We supply Hydroxybupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxybupropion?

Yes. Every lot of Hydroxybupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxybupropion be shipped internationally?

Yes. We export Hydroxybupropion worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.