Threohydro Bupropion

Name: Threohydro Bupropion
Brand: Vaqora Chemicals
SKU: VQ-021923

About Threohydro Bupropion

Listed under CAS 153365-82-3, Threohydro Bupropion is a metabolite or degradation product of Bupropion available from Vaqora Chemicals. Its molecular formula is C13H20ClNO and its molecular weight is 241.76 g/mol. The IUPAC name is (1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol. Alternative names: Threo-Hydroxy Bupropion and Bupropion Dihydro (R,RS)-Isomers (Maleate).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bupropion, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Threohydro Bupropion in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	Threohydro Bupropion
Catalogue No.	VQ-021923
CAS Number	153365-82-3
IUPAC name	(1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol
Molecular formula	C₁₃H₂₀ClNO
Molecular weight	241.76 g/mol
Exact mass	241.1233
Grade	Reference Standard
HSN code	38229090
InChIKey	NDPTTXIBLSWNSF-JOYOIKCWSA-N
SMILES	C[C@@H]([C@H](C1=CC(=CC=C1)Cl)O)NC(C)(C)C
PubChem CID	9834682

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 2
TPSA	32.3 Å²
Synonyms	Threo-Hydroxy Bupropion, Bupropion Dihydro (R,RS)-Isomers (Maleate), Threo Hydroxy Bupropion, Threohydroxy Bupropion, Benzenemethanol, 3-chloro-alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)-, (alphaR)-rel-, rel-(alphaR)-3-Chloro-alpha-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol, rel-(alphaR)-3-Chloro-alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)benzenemethanol, rac threo-Dihydro Bupropion, rac threo-Dihydrobupropion, S,S-threo-Hydrobupropion

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Threohydro Bupropion?

The CAS Registry Number of Threohydro Bupropion is 153365-82-3. It is also known as Threo-Hydroxy Bupropion, Bupropion Dihydro (R,RS)-Isomers (Maleate), Threo Hydroxy Bupropion.

What is the molecular formula and molecular weight of Threohydro Bupropion?

Threohydro Bupropion has the molecular formula C13H20ClNO and a molecular weight of 241.76 g/mol. Its IUPAC name is (1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol.

What is Threohydro Bupropion used for?

Threohydro Bupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Threohydro Bupropion can I order?

We supply Threohydro Bupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Threohydro Bupropion?

Yes. Every lot of Threohydro Bupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Threohydro Bupropion be shipped internationally?

Yes. Threohydro Bupropion is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.