(S,S)-Hydroxy Bupropion

Name: (S,S)-Hydroxy Bupropion
Brand: Vaqora Chemicals
SKU: VQ-021921

About (S,S)-Hydroxy Bupropion

Listed under CAS 192374-14-4, (S,S)-Hydroxy Bupropion is a metabolite or degradation product of Bupropion available from Vaqora Chemicals. With the molecular formula C13H18ClNO2, it has a molar mass of 255.74 g/mol. Systematically, it is named (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol. Alternative names: Radafaxine and (2s,3s)-hydroxybupropion.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Bupropion, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S,S)-Hydroxy Bupropion is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	(S,S)-Hydroxy Bupropion
Catalogue No.	VQ-021921
CAS Number	192374-14-4
IUPAC name	(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Molecular formula	C₁₃H₁₈ClNO₂
Molecular weight	255.74 g/mol
Exact mass	255.1026
Grade	Reference Standard
HSN code	38229090
InChIKey	RCOBKSKAZMVBHT-TVQRCGJNSA-N
SMILES	C[C@H]1[C@@](OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O
PubChem CID	9795056

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 3
TPSA	41.5 Å²
Synonyms	Radafaxine, 2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, (2S,3S)-, (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, (+)-(2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, Hydroxybupropion (as (RS,RS)-cyclic Hemiketal), (2s,3s)-hydroxybupropion, (2S-cis)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol, 2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, (2S-cis)-, (2~{S},3~{S})-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S,S)-Hydroxy Bupropion?

The CAS Registry Number of (S,S)-Hydroxy Bupropion is 192374-14-4. It is also known as Radafaxine, 2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, (2S,3S)-, (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol.

What is the molecular formula and molecular weight of (S,S)-Hydroxy Bupropion?

(S,S)-Hydroxy Bupropion has the molecular formula C13H18ClNO2 and a molecular weight of 255.74 g/mol. Its IUPAC name is (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol.

What is (S,S)-Hydroxy Bupropion used for?

(S,S)-Hydroxy Bupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S,S)-Hydroxy Bupropion can I order?

We supply (S,S)-Hydroxy Bupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S,S)-Hydroxy Bupropion?

Yes. Every lot of (S,S)-Hydroxy Bupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S,S)-Hydroxy Bupropion be shipped internationally?

Yes. We export (S,S)-Hydroxy Bupropion worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.