Tiotropium Bromide Hydrate

Name: Tiotropium Bromide Hydrate
Brand: Vaqora Chemicals
SKU: VQ-043331

About Tiotropium Bromide Hydrate

Listed under CAS 139404-48-1, Tiotropium Bromide Hydrate is a high-purity reference standard of Tiotropium available from Vaqora Chemicals. With the molecular formula C19H24BrNO5S2, it has a molar mass of 490.4 g/mol. It is also known as Tiotropium Bromide Monohydrate or Tiotropium bromide xhydrate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Tiotropium standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Tiotropium Bromide Hydrate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tiotropium

View every impurity, metabolite and intermediate we list for Tiotropium.

Tiotropium impurities

Specifications & identifiers

Chemical identifiers
Product name	Tiotropium Bromide Hydrate
Catalogue No.	VQ-043331
CAS Number	139404-48-1
IUPAC name	[(1R,2R,4S,5S)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate;bromide;hydrate
Molecular formula	C₁₉H₂₄BrNO₅S₂
Molecular weight	490.4 g/mol
Exact mass	489.0279
Grade	Reference Standard
HSN code	38229090
InChIKey	MQLXPRBEAHBZTK-KFEMZTBUSA-M
SMILES	C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)C(C4=CC=CS4)(C5=CC=CS5)O)C.O.[Br-]
PubChem CID	11431811

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 8
TPSA	117 Å²
Synonyms	Tiotropium Bromide Monohydrate, Tiotropium bromide xhydrate, Spiriva Respimat, Tiotropium Bromide hydrate (BA679BR), Tiotropium bromide anhydrous, BA-679BR, BA 679 BR, BA-679 BR, BA-679-BR, Bromuro de tiotropio, Bromure de tiotropium

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tiotropium Bromide Hydrate?

The CAS Registry Number of Tiotropium Bromide Hydrate is 139404-48-1. It is also known as Tiotropium Bromide Monohydrate, Tiotropium bromide xhydrate, Spiriva Respimat.

What is the molecular formula and molecular weight of Tiotropium Bromide Hydrate?

Tiotropium Bromide Hydrate has the molecular formula C19H24BrNO5S2 and a molecular weight of 490.4 g/mol.

What is Tiotropium Bromide Hydrate used for?

Tiotropium Bromide Hydrate is supplied as a characterised reference material related to Tiotropium. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tiotropium Bromide Hydrate can I order?

We supply Tiotropium Bromide Hydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tiotropium Bromide Hydrate?

Yes. Every lot of Tiotropium Bromide Hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tiotropium Bromide Hydrate be shipped internationally?

Yes. Tiotropium Bromide Hydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.