Leflunomide EP Impurity A

Name: Leflunomide EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-022939

About Leflunomide EP Impurity A

Leflunomide EP Impurity A is a pharmacopeial impurity of Leflunomide carrying the CAS registry number 455-14-1. The compound has the formula C7H6F3N, corresponding to a molecular weight of 161.12 g/mol. Its systematic (IUPAC) name is 4-(trifluoromethyl)aniline. It is also known as Leflunomide - Impurity A or 4-Aminobenzotrifluoride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Leflunomide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Leflunomide

View every impurity, metabolite and intermediate we list for Leflunomide.

Leflunomide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Leflunomide EP Impurity A
Catalogue No.	VQ-022939
CAS Number	455-14-1
IUPAC name	4-(trifluoromethyl)aniline
Molecular formula	C₇H₆F₃N
Molecular weight	161.12 g/mol
Exact mass	161.0452
Grade	Reference Standard
HSN code	38229090
InChIKey	ODGIMMLDVSWADK-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(F)(F)F)N
PubChem CID	9964

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 4
TPSA	26 Å²
Synonyms	Leflunomide - Impurity A, 4-Aminobenzotrifluoride, 4-Trifluoromethylaniline, p-Aminobenzotrifluoride, Benzenamine, 4-(trifluoromethyl)-, p-(Trifluoromethyl)aniline, alpha,alpha,alpha-Trifluoro-p-toluidine, para-trifluoromethylaniline, alpha,alpha,alpha-Trifluoro-p-anisidine, p-Trifluoromethylaniline, 4-(Trifluoromethyl)benzenamine, Aniline, p-(trifluoromethyl)-

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H318Causes serious eye damage
H319Causes serious eye irritation
H331Toxic if inhaled
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P321, P330, P337 + P317, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leflunomide EP Impurity A?

The CAS Registry Number of Leflunomide EP Impurity A is 455-14-1. It is also known as Leflunomide - Impurity A, 4-Aminobenzotrifluoride, 4-Trifluoromethylaniline.

What is the molecular formula and molecular weight of Leflunomide EP Impurity A?

Leflunomide EP Impurity A has the molecular formula C7H6F3N and a molecular weight of 161.12 g/mol. Its IUPAC name is 4-(trifluoromethyl)aniline.

What is Leflunomide EP Impurity A used for?

Leflunomide EP Impurity A is supplied as a characterised reference material related to Leflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leflunomide EP Impurity A can I order?

We supply Leflunomide EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leflunomide EP Impurity A?

Yes. Every lot of Leflunomide EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leflunomide EP Impurity A be shipped internationally?

Yes. Leflunomide EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.