Leflunomide EP Impurity H

Name: Leflunomide EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-022941

About Leflunomide EP Impurity H

Leflunomide EP Impurity H (CAS 24522-30-3) is a pharmacopeial impurity of Leflunomide offered by Vaqora Chemicals. Its molecular formula is C10H7F3N2O and its molecular weight is 228.17 g/mol. Its systematic (IUPAC) name is 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide. Alternative names: Leflunomide - Impurity H and Teriflunomide EP Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Leflunomide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Leflunomide EP Impurity H in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Leflunomide

View every impurity, metabolite and intermediate we list for Leflunomide.

Leflunomide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Leflunomide EP Impurity H
Catalogue No.	VQ-022941
CAS Number	24522-30-3
IUPAC name	2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
Molecular formula	C₁₀H₇F₃N₂O
Molecular weight	228.17 g/mol
Exact mass	228.051
Grade	Reference Standard
HSN code	38229090
InChIKey	JBNCFFDGYDZEEN-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(F)(F)F)NC(=O)CC#N
PubChem CID	3823803

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	1 / 5
TPSA	52.9 Å²
Synonyms	Leflunomide - Impurity H, Teriflunomide EP Impurity B, 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide, Acetamide, 2-cyano-N-[4-(trifluoromethyl)phenyl]-, Acetamide, 2-cyano-N-(4-(trifluoromethyl)phenyl)-, p-Acetotoluidide, 2-cyano-alpha,alpha,alpha-trifluoro-, Leflunomide Impurity H, Acetamide,2-cyano-N-[4-(trifluoromethyl)phenyl]-, 2-cyano-n-[4-(trifluoromethyl) phenyl]acetamide, 2-Cyano-N-[4-(trifluoromethyl)phenyl]- acetamide, 4'-trifluoromethyl-cyanoacetanilide, CS-M2760

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leflunomide EP Impurity H?

The CAS Registry Number of Leflunomide EP Impurity H is 24522-30-3. It is also known as Leflunomide - Impurity H, Teriflunomide EP Impurity B, 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide.

What is the molecular formula and molecular weight of Leflunomide EP Impurity H?

Leflunomide EP Impurity H has the molecular formula C10H7F3N2O and a molecular weight of 228.17 g/mol. Its IUPAC name is 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide.

What is Leflunomide EP Impurity H used for?

Leflunomide EP Impurity H is supplied as a characterised reference material related to Leflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leflunomide EP Impurity H can I order?

We supply Leflunomide EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leflunomide EP Impurity H?

Yes. Every lot of Leflunomide EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leflunomide EP Impurity H be shipped internationally?

Yes. Leflunomide EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.