Leuprolide EP Impurity B

Name: Leuprolide EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-006459

About Leuprolide EP Impurity B

Leuprolide EP Impurity B (CAS 112642-11-2) is a pharmacopeial impurity of Leuprolide offered by Vaqora Chemicals. Formula C59H84N16O12, molecular weight 1209.4 g/mol. It is also known as (D-His2)-Leuprolide or (Des-Gly10,D-His2,D-Leu6,Pro-NHEt9)-LHRH.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Leuprolide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Leuprolide EP Impurity B in 10 mg, 25 mg and 50 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Leuprolide

View every impurity, metabolite and intermediate we list for Leuprolide.

Leuprolide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Leuprolide EP Impurity B
Catalogue No.	VQ-006459
CAS Number	112642-11-2
IUPAC name	(2S)-N-[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular formula	C₅₉H₈₄N₁₆O₁₂
Molecular weight	1209.4 g/mol
Exact mass	1208.6455
Grade	Reference Standard
HSN code	38229090
InChIKey	GFIJNRVAKGFPGQ-JFMQHNAUSA-N
SMILES	CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
PubChem CID	131676671

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	15 / 14
TPSA	432 Å²
Synonyms	(D-His2)-Leuprolide, (Des-Gly10,D-His2,D-Leu6,Pro-NHEt9)-LHRH, (D-His2)-Leuprolide Trifluoroacetic Acid Salt, Leuprorelin Impurity N8, Leuprorelin impurity 37, pE-(dH)WSY(dL)LRP-NHEt, 112642-11-2free base, Leuprolide(Leuprorelin) EP Impurity B, Pyr-D-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt, (Des-Gly10,D-His2,D-Leu6,Pro-NHEt 9)-LHRH

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leuprolide EP Impurity B?

The CAS Registry Number of Leuprolide EP Impurity B is 112642-11-2. It is also known as (D-His2)-Leuprolide, (Des-Gly10,D-His2,D-Leu6,Pro-NHEt9)-LHRH, (D-His2)-Leuprolide Trifluoroacetic Acid Salt.

What is the molecular formula and molecular weight of Leuprolide EP Impurity B?

Leuprolide EP Impurity B has the molecular formula C59H84N16O12 and a molecular weight of 1209.4 g/mol.

What is Leuprolide EP Impurity B used for?

Leuprolide EP Impurity B is supplied as a characterised reference material related to Leuprolide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leuprolide EP Impurity B can I order?

We supply Leuprolide EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leuprolide EP Impurity B?

Yes. Every lot of Leuprolide EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leuprolide EP Impurity B be shipped internationally?

Yes. We export Leuprolide EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.