Nintedanib Intermediate 1

Name: Nintedanib Intermediate 1
Brand: Vaqora Chemicals
SKU: VQ-013659

About Nintedanib Intermediate 1

Nintedanib Intermediate 1 (CAS 262368-30-9) is a process intermediate or related compound of Nintedanib offered by Vaqora Chemicals. Its molecular formula is C14H22N4O and its molecular weight is 262.35 g/mol. The IUPAC name is N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide. Common synonyms include CS-M0380 and US10981896, Compound 14.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Nintedanib, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib Intermediate 1
Catalogue No.	VQ-013659
CAS Number	262368-30-9
IUPAC name	N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
Molecular formula	C₁₄H₂₂N₄O
Molecular weight	262.35 g/mol
Exact mass	262.1794
Grade	Reference Standard
HSN code	2933
InChIKey	LBWNQLVDYPNHAV-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N
PubChem CID	21927707

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	1 / 4
TPSA	52.8 Å²
Synonyms	N-(4-Aminophenyl)-N,4-dimethyl-1-piperazineacetamide, N-[[(4-Methylpiperazin-1-yl)methyl]carbonyl]-N-methyl-p-phenylenediamine, 1-Piperazineacetamide, N-(4-aminophenyl)-N,4-dimethyl-, CS-M0380, N-(4-Aminophenyl)-N-methyl-2-(4-methyl-1-piperazinyl)acetamide, US10981896, Compound 14, N-(4-aminophenyl)-N-methyl-2-(4-methylpip, 4-[N-(N-methylpiperazinomethylcarbonyl)-N-methyl-amino]-aniline, n-[(4-methyl-piperazin-1-yl)-methylcarbonyl]-n-methyl-p-phenylendiamine, N-[(4-methyl-piperazin-1-yl)-methylcarbonyl]-N-methyl-p-phenylenediamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib Intermediate 1?

The CAS Registry Number of Nintedanib Intermediate 1 is 262368-30-9. It is also known as N-(4-Aminophenyl)-N,4-dimethyl-1-piperazineacetamide, N-[[(4-Methylpiperazin-1-yl)methyl]carbonyl]-N-methyl-p-phenylenediamine, 1-Piperazineacetamide, N-(4-aminophenyl)-N,4-dimethyl-.

What is the molecular formula and molecular weight of Nintedanib Intermediate 1?

Nintedanib Intermediate 1 has the molecular formula C14H22N4O and a molecular weight of 262.35 g/mol. Its IUPAC name is N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide.

What is Nintedanib Intermediate 1 used for?

Nintedanib Intermediate 1 is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib Intermediate 1 can I order?

We supply Nintedanib Intermediate 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib Intermediate 1?

Yes. Every lot of Nintedanib Intermediate 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib Intermediate 1 be shipped internationally?

Yes. Nintedanib Intermediate 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.