Nintedanib Intermediate 2

Name: Nintedanib Intermediate 2
Brand: Vaqora Chemicals
SKU: VQ-013660

About Nintedanib Intermediate 2

Vaqora Chemicals supplies Nintedanib Intermediate 2, a process intermediate or related compound of Nintedanib registered under CAS number 1168150-46-6. With the molecular formula C18H15NO4, it has a molar mass of 309.3 g/mol. Systematically, it is named methyl (3E)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Nintedanib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Nintedanib Intermediate 2 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib Intermediate 2
Catalogue No.	VQ-013660
CAS Number	1168150-46-6
IUPAC name	methyl (3E)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate
Molecular formula	C₁₈H₁₅NO₄
Molecular weight	309.3 g/mol
Exact mass	309.1001
Grade	Reference Standard
HSN code	2933
InChIKey	WUVZENIISJMEHI-FOCLMDBBSA-N
SMILES	CO/C(=C/1\C2=C(C=C(C=C2)C(=O)OC)NC1=O)/C3=CC=CC=C3
PubChem CID	42634134

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 4
TPSA	64.6 Å²
Synonyms	(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester, Methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (3E)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate, (E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (E)-3-[Methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate, methyl (3E)-3-[methoxy(phenyl)methylene]-2-oxo-indoline-6-carboxylate, Methyl (3E)-3-[methoxy(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate, (E)-methyl3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib Intermediate 2?

The CAS Registry Number of Nintedanib Intermediate 2 is 1168150-46-6. It is also known as (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester, Methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (3E)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate.

What is the molecular formula and molecular weight of Nintedanib Intermediate 2?

Nintedanib Intermediate 2 has the molecular formula C18H15NO4 and a molecular weight of 309.3 g/mol. Its IUPAC name is methyl (3E)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate.

What is Nintedanib Intermediate 2 used for?

Nintedanib Intermediate 2 is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib Intermediate 2 can I order?

We supply Nintedanib Intermediate 2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib Intermediate 2?

Yes. Every lot of Nintedanib Intermediate 2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib Intermediate 2 be shipped internationally?

Yes. We export Nintedanib Intermediate 2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.