Nintedanib N-Methyl Aniline Intermediate (Sta… 474020-88-7

Name: Nintedanib N-Methyl Aniline Intermediate (Stage-I)
Brand: Vaqora Chemicals
SKU: VQ-013664

About Nintedanib N-Methyl Aniline Intermediate (Stage-I)

Vaqora Chemicals supplies Nintedanib N-Methyl Aniline Intermediate (Stage-I), a process intermediate or related compound of Nintedanib registered under CAS number 474020-88-7 at a purity of 99.19%. Its molecular formula is C12H16N2O4 and its molecular weight is 252.27 g/mol. The IUPAC name is tert-butyl N-methyl-N-(4-nitrophenyl)carbamate. It is also known as tert-Butyl N-methyl(4-nitrophenyl)carbamate or Tert-butyl methyl(4-nitrophenyl)carbamate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Nintedanib, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nintedanib N-Methyl Aniline Intermediate (Stage-I) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib N-Methyl Aniline Intermediate (Stage-I)
Catalogue No.	VQ-013664
CAS Number	474020-88-7
IUPAC name	tert-butyl N-methyl-N-(4-nitrophenyl)carbamate
Molecular formula	C₁₂H₁₆N₂O₄
Molecular weight	252.27 g/mol
Exact mass	252.111
Grade	Reference Standard
Purity / assay	99.19%
HSN code	2933
InChIKey	FKIOMBZTRAZEBX-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N(C)C1=CC=C(C=C1)[N+](=O)[O-]
PubChem CID	58263718

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	0 / 4
TPSA	75.4 Å²
Synonyms	1,1-Dimethylethyl N-methyl-N-(4-nitrophenyl)carbamate, tert-Butyl N-methyl(4-nitrophenyl)carbamate, Tert-butyl methyl(4-nitrophenyl)carbamate, tert-Butyl methyl 4-nitrophenylcarbamate, Carbamic acid, methyl(4-nitrophenyl)-, 1,1-dimethylethyl ester (9CI), Carbamic acid, methyl(4-nitrophenyl)-, 1,1-dimethylethyl ester, t-Butyl methyl 4-nitrophenylcarbamate, N-BOC-N-methyl-4-nitroaniline, CS-B1645, 1-(Boc-methylamino)-4-nitrobenzene, tert-butyl methyl4-nitrophenylcarbamate, N-methyl-N-(4-nitrophenyl)carbamic acid tert-butyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib N-Methyl Aniline Intermediate (Stage-I)?

The CAS Registry Number of Nintedanib N-Methyl Aniline Intermediate (Stage-I) is 474020-88-7. It is also known as 1,1-Dimethylethyl N-methyl-N-(4-nitrophenyl)carbamate, tert-Butyl N-methyl(4-nitrophenyl)carbamate, Tert-butyl methyl(4-nitrophenyl)carbamate.

What is the molecular formula and molecular weight of Nintedanib N-Methyl Aniline Intermediate (Stage-I)?

Nintedanib N-Methyl Aniline Intermediate (Stage-I) has the molecular formula C12H16N2O4 and a molecular weight of 252.27 g/mol. Its IUPAC name is tert-butyl N-methyl-N-(4-nitrophenyl)carbamate.

What is Nintedanib N-Methyl Aniline Intermediate (Stage-I) used for?

Nintedanib N-Methyl Aniline Intermediate (Stage-I) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib N-Methyl Aniline Intermediate (Stage-I) can I order?

We supply Nintedanib N-Methyl Aniline Intermediate (Stage-I) in Reference Standard (99.19%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib N-Methyl Aniline Intermediate (Stage-I)?

Yes. Every lot of Nintedanib N-Methyl Aniline Intermediate (Stage-I) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib N-Methyl Aniline Intermediate (Stage-I) be shipped internationally?

Yes. We export Nintedanib N-Methyl Aniline Intermediate (Stage-I) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.