Paroxetine Hydrochloride HemiHydrate EP Impur… 127017-74-7

Name: Paroxetine Hydrochloride HemiHydrate EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-021306

About Paroxetine Hydrochloride HemiHydrate EP Impurity B

Vaqora Chemicals supplies Paroxetine Hydrochloride HemiHydrate EP Impurity B, a pharmacopeial impurity of Paroxetine registered under CAS number 127017-74-7. Its molecular formula is C20H24ClNO4 and its molecular weight is 377.9 g/mol. Alternative names: Paroxetine Hemihydrate EP Impurity B and Paroxetine - Impurity B (Hydrochloride Salt).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Paroxetine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Paroxetine Hydrochloride HemiHydrate EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Paroxetine

View every impurity, metabolite and intermediate we list for Paroxetine.

Paroxetine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Paroxetine Hydrochloride HemiHydrate EP Impurity B
Catalogue No.	VQ-021306
CAS Number	127017-74-7
IUPAC name	(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-methoxyphenyl)piperidine;hydrochloride
Molecular formula	C₂₀H₂₄ClNO₄
Molecular weight	377.9 g/mol
Exact mass	377.1394
Grade	Reference Standard
HSN code	38229090
InChIKey	WGRXGIJCIOCNHB-NKGQWRHHSA-N
SMILES	COC1=CC=C(C=C1)[C@@H]2CCNC[C@H]2COC3=CC4=C(C=C3)OCO4.Cl
PubChem CID	71315281

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	49 Å²
Synonyms	rac-trans-4-Defluoro-4-methoxy Paroxetine Hydrochloride, Rel-Paroxetine hydrochloride hemihydrate EP Impurity B HCl, Paroxetine Hydrochloride Hemihydrate EP Impurity B Hydrochloride, Paroxetine Hydrochloride Hemihydrate EP Impurity B, 4-Methoxy Paroxetine Hydrochloride, Paroxetine Hemihydrate EP Impurity B, Paroxetine - Impurity B (Hydrochloride Salt), trans-3S-Defluoro-4-methoxy Paroxetine Hydrochloride, (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-methoxyphenyl)piperidine hydrochloride, (3S,4R)-3-((Benzodioxol-5-yloxy)methyl)-4-(4-methoxyphenyl)piperidine hydrochloride, 3-((Benzodioxol-5-yloxy)methyl)-4-(4-methoxyphenyl)piperidine hydrochloride, (3S,4R)-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P304 + P340, P305 + P351 + P338, P318, P319, P330, P337 + P317, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Paroxetine Hydrochloride HemiHydrate EP Impurity B?

The CAS Registry Number of Paroxetine Hydrochloride HemiHydrate EP Impurity B is 127017-74-7. It is also known as rac-trans-4-Defluoro-4-methoxy Paroxetine Hydrochloride, Rel-Paroxetine hydrochloride hemihydrate EP Impurity B HCl, Paroxetine Hydrochloride Hemihydrate EP Impurity B Hydrochloride.

What is the molecular formula and molecular weight of Paroxetine Hydrochloride HemiHydrate EP Impurity B?

Paroxetine Hydrochloride HemiHydrate EP Impurity B has the molecular formula C20H24ClNO4 and a molecular weight of 377.9 g/mol.

What is Paroxetine Hydrochloride HemiHydrate EP Impurity B used for?

Paroxetine Hydrochloride HemiHydrate EP Impurity B is supplied as a characterised reference material related to Paroxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Paroxetine Hydrochloride HemiHydrate EP Impurity B can I order?

We supply Paroxetine Hydrochloride HemiHydrate EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Paroxetine Hydrochloride HemiHydrate EP Impurity B?

Yes. Every lot of Paroxetine Hydrochloride HemiHydrate EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Paroxetine Hydrochloride HemiHydrate EP Impurity B be shipped internationally?

Yes. Paroxetine Hydrochloride HemiHydrate EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.